Evidence map›Paper›PMID 38503628›Full record

Observational studyJournal of cardiothoracic and vascular anesthesia2024

Impact of Pressure Recovery Adjustment on Aortic Valve Area Classification of Disease Severity in Transcatheter Aortic Valve Replacement Patients.

Luis F Gonzalez-Ciccarelli, Renan A Ferrufino, Abdulaziz Alfadhel, Ethan Brovman, Jamel Ortoleva, Benjamin S Wessler, Michael Fettiplace, Frederick Cobey

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of cardiothoracic and vascular anesthesia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Luis F Gonzalez-CiccarelliDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Renan A FerrufinoDepartment of Anesthesiology and Perioperative Medicine, Tufts Medical Center, Boston, MA. Electronic address: rferrufino@tuftsmedicalcenter.org.
Abdulaziz AlfadhelDepartment of Anesthesiology. King Saud University College of Medicine, Riyadh, Kingdom of Saudi Arabia.
Ethan BrovmanDepartment of Anesthesiology and Perioperative Medicine, Tufts Medical Center, Boston, MA.
Jamel OrtolevaDepartment of Anesthesiology, Boston Medical Center, Boston, MA.
Benjamin S WesslerCardiovascular Center, Division of Cardiology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA.
Michael FettiplaceDepartment of Anesthesiology, University of Illinois Health, Chicago, IL.
Frederick CobeyDepartment of Anesthesiology and Perioperative Medicine, Tufts Medical Center, Boston, MA.
Tufts Medical Center · USBoston Medical Center · USBrigham and Women's Hospital · USKing Saud University · SATufts University · USUniversity of Illinois Chicago · US

Funding

Tufts Clinical and Translational Science Institute (Clinical Trial Design Labs Supplement)UM1TR004398 · NCATS · TUFTS UNIVERSITY BOSTON · PI Harry P. Selker · 2023 to 2026
$44.5M
Palliative Care for High-Risk TAVR Patients: The Impact of MultimorbidityK23AG055667 · NIA · TUFTS MEDICAL CENTER · PI WESSLER, BENJAMIN SETH · 2018 to 2022
$948k
NIA NIH HHS K23 AG055667
6 · The paper itself

Abstract

objectivesTo determine the impact of pressure recovery (PR) adjustment on disease severity grading in patients with severe aortic stenosis. The authors hypothesized that accounting for PR would result in echocardiographic reclassification of aortic stenosis severity in a significant number of patients.

designA retrospective observational study between October 2013 and February 2021.

settingA single-center, quaternary-care academic center.

participantsAdults (≥18 years old) who underwent transcatheter aortic valve implantation (TAVI).

interventionsTAVI. MEASUREMENTS AND MAIN

resultsA total of 342 patients were evaluated in this study. Left ventricle mass index was significantly greater in patients who continued to be severe after PR (100.47 ± 28.77 v 90.15 ± 24.03, p = < 0.000001). Using PR-adjusted aortic valve area (AVA) resulted in the reclassification of 81 patients (24%) from severe to moderate aortic stenosis (AVA >1.0 cm

conclusionAdjusting calculated AVA for PR resulted in a reclassification of a significant number of adult patients from severe to moderate aortic stenosis. PR was significantly larger in patients who reclassified from severe to moderate aortic stenosis after adjusting for PR. PR appeared to remain relevant in patients with STJ ≥3.0 cm. Clinicians need to be aware of PR and how to account for its effect when measuring pressure gradients with Doppler.

Indexed as

Aortic ValveAortic Valve StenosisSeverity of Illness IndexTranscatheter Aortic Valve ReplacementAgedAged, 80 and overEchocardiographyFemaleHumansMaleRetrospective Studiesenergy lossenergy loss coefficientpressure recoverysevere aortic stenosistranscatheter aortic valve replacementvalvulo-arterial impedance

Identifiers

PMID38503628
PMCPMC11996196
OpenAlexW4392284120

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.