Evidence map›Paper›PMID 38503548›Full record

ArticleInternational journal of epidemiology2024

Prenatal cannabis use disorder and gastroschisis in California, 2007-19.

Erin Delker, Rebecca J Baer, Ann E Kelly, Christina Chambers, Gretchen Bandoli

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Erin DelkerDepartment of Pediatrics, University of California San Diego, San Diego, CA, USA.ORCID 0000-0001-6490-2570
Rebecca J BaerDepartment of Pediatrics, University of California San Diego, San Diego, CA, USA.
Ann E KellyDepartment of Pediatrics, University of California San Diego, San Diego, CA, USA.
Christina ChambersDepartment of Pediatrics, University of California San Diego, San Diego, CA, USA.
Gretchen BandoliDepartment of Pediatrics, University of California San Diego, San Diego, CA, USA.
University of California San Diego · USUniversity of California, San Francisco · US

Funding

Applying Machine Learning in the Prediction and Identification of Children Affected by Prenatal Alcohol ExposureK01AA027811 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BANDOLI, GRETCHEN E. · 2019 to 2023
$865k
NIAAA NIH HHS K01 AA027811
6 · The paper itself

Abstract

backgroundGastroschisis is a congenital anomaly of the abdominal wall with an unknown aetiology. Recent trends in the prevalence of gastroschisis suggest that changing environmental or behavioural factors may contribute. We examined whether prenatal cannabis use disorder was associated with gastroschisis.

methodsThe Study of Outcomes of Mothers and Infants is a population-based cohort compiled of California birth records that have been linked to Department of Health Care Access and Information hospitalization, emergency department and ambulatory surgery records. We included 2007-19 singleton live births (n = 5 774 656). Cannabis use disorder was measured by diagnosis codes at any visit during pregnancy or at birth. Gastroschisis was measured by diagnosis or surgical repair procedure codes at birth or during the first year of life.

resultsThe prevalence of cannabis use disorder was about 1%. The prevalence of gastroschisis was 0.14% and 0.06% among those with and without cannabis use disorder, respectively. There were positive associations between cannabis use disorder and gastroschisis when using a multivariable model [adjusted risk ratio (aRR) = 1.3, 95% confidence interval (CI) 1.0, 1.7) and a matched sample approach (aRR = 1.5, 95% CI 1.1, 2.1). The association varied by maternal age and was largest among people aged >34 years (aRR = 2.5, 95% CI 1.0, 5.8).

conclusionsWe confirm findings of a positive association between cannabis exposure and gastroschisis and add that it is strongest when maternal age is greater than 34 years. More investigation into whether the association is causal, and why the association varies by maternal age, is encouraged.

Indexed as

GastroschisisMarijuana AbuseSubstance-Related DisordersCaliforniaFemaleHumansInfantInfant, NewbornMaternal AgePregnancyPrevalenceRisk Factorsbirth defectCannabisgastroschisissibling design

Identifiers

PMID38503548
PMCPMC11491667
OpenAlexW4394767794

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.