Evidence map›Paper›PMID 38503334›Full record

ArticleProceedings. Biological sciences2024

Human brains preserve in diverse environments for at least 12 000 years.

Alexandra L Morton-Hayward, Ross P Anderson, Erin E Saupe, Greger Larson, Julie G Cosmidis

Abstract read
In one paragraph

Article in Proceedings. Biological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexandra L Morton-HaywardDepartment of Earth Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-0711-8381
Ross P AndersonDepartment of Earth Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-0558-7563
Erin E SaupeDepartment of Earth Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-0370-9897
Greger LarsonPalaeogenomics and Bio-Archaeology Research Network, School of Archaeology, University of Oxford, Oxford, UK.ORCID 0000-0002-4092-0392
Julie G CosmidisDepartment of Earth Sciences, University of Oxford, Oxford, UK.

Funding

All Souls CollegeAnglo-Danish Society. R.P.ALeverhulme PrizeNatural Environment Research CouncilRoyal Society
6 · The paper itself

Abstract

The brain is thought to be among the first human organs to decompose after death. The discovery of brains preserved in the archaeological record is therefore regarded as unusual. Although mechanisms such as dehydration, freezing, saponification, and tanning are known to allow for the preservation of the brain on short time scales in association with other soft tissues (≲4000 years), discoveries of older brains, especially in the absence of other soft tissues, are rare. Here, we collated an archive of more than 4400 human brains preserved in the archaeological record across approximately 12 000 years, more than 1300 of which constitute the only soft tissue preserved amongst otherwise skeletonized remains. We found that brains of this type persist on time scales exceeding those preserved by other means, which suggests an unknown mechanism may be responsible for preservation particular to the central nervous system. The untapped archive of preserved ancient brains represents an opportunity for bioarchaeological studies of human evolution, health and disease.

Indexed as

BrainCentral Nervous SystemHeadHumansbioarchaeologybraindiagenesisforensic anthropologysoft tissue preservationtaphonomy

Identifiers

PMID38503334
PMCPMC10950470

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.