Evidence map›Paper›PMID 38502701›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses.

Takafumi Shichijo, Jun-Ichirou Yasunaga, Kei Sato, Kisato Nosaka, Kosuke Toyoda, Miho Watanabe, Wenyi Zhang, Yoshio Koyanagi, Edward L Murphy, Roberta L Bruhn and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  10. JunB-HBZ nuclear translocation by TGF-β is a key driver in HTLV-1-mediated leukemogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Viral oncogenesis in cancer: from mechanisms to therapeutics.Signal transduction and targeted therapy · 2025
    Review
  12. Article
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  17. Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Takafumi ShichijoDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0002-1272-3738
Jun-Ichirou YasunagaDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0002-7939-2080
Kei SatoDivision of Systems Virology, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.ORCID 0000-0003-4431-1380
Kisato NosakaDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0001-6682-2451
Kosuke ToyodaDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0001-8125-4528
Miho WatanabeDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0009-0002-0764-2287
Wenyi ZhangDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0009-0006-9885-411X
Yoshio KoyanagiLaboratory of Systems Virology, Institute for Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Edward L MurphyDepartment of Laboratory Medicine, University of California, San Francisco 94158.ORCID 0000-0001-6515-3989
Roberta L BruhnVitalant Research Institute, San Francisco 94105.ORCID 0000-0002-5898-8168
Ki-Ryang KohDepartment of Hematology, Osaka General Hospital of West Japan Railway Company, Osaka 545-0053, Japan.
Hirofumi AkariCenter for the Evolutionary Origins of Human Behavior, Kyoto University, Inuyama, Aichi 484-8506, Japan.ORCID 0000-0003-2166-6015
Terumasa IkedaDivision of Molecular Virology and Genetics, Joint Research Center for Human Retrovirus infection, Kumamoto University, Kumamoto 860-0811, Japan.ORCID 0000-0003-2869-9450
Reuben S HarrisDepartment of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, TX 78229.ORCID 0000-0002-9034-9112
Patrick L GreenCenter for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.ORCID 0000-0002-0204-562X
Masao MatsuokaDepartment of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0002-0473-754X
Kyoto University · JPKumamoto University · JPThe University of Texas Health Science Center at San Antonio · USJapan Science and Technology Agency · JPPacific Research Institute · USThe Ohio State University · USUniversity of California, San Francisco · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Role of Inflammation in Tax-mediated TumorigenesisP01CA100730 · NCI · WASHINGTON UNIVERSITY · PI Lee Ratner · 2003 to 2026
$44.8M
PROJECT 3 – BIOLOGY OF DNA DEAMINASES IN CANCERP01CA234228 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Rommie E Amaro · 2019 to 2026
$14.5M
NCI NIH HHS P01 CA100730NCI NIH HHS P01 CA234228NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

Human retroviruses are derived from simian ones through cross-species transmission. These retroviruses are associated with little pathogenicity in their natural hosts, but in humans, HIV causes AIDS, and human T-cell leukemia virus type 1 (HTLV-1) induces adult T-cell leukemia-lymphoma (ATL). We analyzed the proviral sequences of HTLV-1, HTLV-2, and simian T-cell leukemia virus type 1 (STLV-1) from Japanese macaques (

Indexed as

Human T-lymphotropic virus 1Leukemia-Lymphoma, Adult T-CellAPOBEC-3G DeaminaseBasic-Leucine Zipper Transcription FactorsCell LineHumansProvirusesTransforming Growth Factor betaVirulenceAPOBEC-3G DeaminaseAPOBEC3G protein, humanBasic-Leucine Zipper Transcription FactorsTransforming Growth Factor betaAPOBEC3GdeltaretrovirusHBZHTLV-1TGF-β

Identifiers

PMID38502701
PMCPMC10990082
OpenAlexW4392946397

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.