Evidence map›Paper›PMID 38502695›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Phenotypic screen of sixty-eight colorectal cancer cell lines identifies CEACAM6 and CEACAM5 as markers of acid resistance.

Johanna Michl, Bobby White, Stefania Monterisi, Walter F Bodmer, Pawel Swietach

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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  11. Goblet cell differentiation subgroups in colorectal cancer.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Johanna MichlDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom.
Bobby White *Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom.
Stefania Monterisi *Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom.
Walter F BodmerDepartment of Oncology, University of Oxford, Oxford OX3 7DQ, United Kingdom.ORCID 0000-0001-6244-9792
Pawel SwietachDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom.ORCID 0000-0002-9945-9473
University of Oxford · GB

Funding

EC | European Research Council (ERC) 723997
6 · The paper itself

Abstract

Elevated cancer metabolism releases lactic acid and CO

Indexed as

AcidosisColorectal NeoplasmsAntigens, CDCarcinoembryonic AntigenCell Adhesion MoleculesCell Line, TumorGPI-Linked ProteinsHumansPhenotypeSignal TransductionTumor MicroenvironmentAntigens, CDCarcinoembryonic AntigenCEACAM5 protein, humanCEACAM6 protein, humanCell Adhesion MoleculesGPI-Linked Proteinsacid–baseacidosismetabolismmicroenvironmenttumor acidity

Identifiers

PMID38502695
PMCPMC10990159
OpenAlexW4392946441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.