Evidence map›Paper›PMID 38502383›Full record

Trial reportProbiotics and antimicrobial proteins2025

Evaluating the Role of Postbiotics in the Modulation of Human Oral Microbiota: A Randomized Controlled Clinical Trial.

Wen Rui, Saiwei Zhong, Xiaoqian Li, Xuna Tang, Lijun Wang, Jingpeng Yang

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. A Novel Postbiotic Reduces Canine Halitosis.Animals : an open access journal from MDPI · 2025
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wen Rui *School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China.
Saiwei Zhong *School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China.
Xiaoqian Li *School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China.
Xuna TangDepartment of Endodontology, Affiliated Hospital of Medical School, Nanjing Stomatological Hospital, Nanjing University, Nanjing, China. xunatang@126.com.
Lijun WangDepartment of Endodontology, Affiliated Hospital of Medical School, Nanjing Stomatological Hospital, Nanjing University, Nanjing, China. wlijun2018@163.com.
Jingpeng YangSchool of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China. yang_jp008@163.com.ORCID http://orcid.org/0000-0002-0802-2891

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a lack of clinical data to support the effectiveness and safety of postbiotics in the modulation of human oral microbiota and oral health care. Here, volunteers were recruited and randomly assigned to two cohorts: a placebo group (n = 15) and a postbiotic group (n = 16). The placebo group used toothpaste that did not contain postbiotics, while the postbiotic group used toothpaste with postbiotics (3 × 10

Indexed as

MicrobiotaMouthProbioticsAdultBacteriaFatty Acids, VolatileFemaleHumansImmunoglobulin ALactobacillusMaleSalivaToothpastesYoung AdultFatty Acids, VolatileImmunoglobulin AToothpastesIgALactobacillus salivariusOral microbiotaPostbioticsShort-chain fatty acids (SCFAs)

Identifiers

PMID38502383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.