Evidence map›Paper›PMID 38502372›Full record

ArticleIn vitro cellular & developmental biology. Animal2024

In vitro generation of epidermal keratinocytes from human CD34-positive hematopoietic stem cells.

Kodavala Sireesha, Echambadi Loganathan Samundeshwari, Kattaru Surekha, Chodimella Chandrasekhar, Potukuchi Venkata Gurunadha Krishna Sarma

Abstract read
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In one paragraph

Article in In vitro cellular & developmental biology. Animal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kodavala SireeshaDepartment of Biotechnology, Sri Venkateswara Institute of Medical Sciences and University, Tirupati, 517507, Andhra Pradesh, India.
Echambadi Loganathan SamundeshwariDepartment of Biotechnology, Sri Venkateswara Institute of Medical Sciences and University, Tirupati, 517507, Andhra Pradesh, India.
Kattaru SurekhaDepartment of Biotechnology, Sri Venkateswara Institute of Medical Sciences and University, Tirupati, 517507, Andhra Pradesh, India.
Chodimella ChandrasekharDepartment of Hematology, Sri Venkateswara Institute of Medical Sciences, Tirupati, 517507, Andhra Pradesh, India.
Potukuchi Venkata Gurunadha Krishna SarmaDepartment of Biotechnology, Sri Venkateswara Institute of Medical Sciences and University, Tirupati, 517507, Andhra Pradesh, India. sarmasvims@gmail.com.ORCID http://orcid.org/0000-0001-9991-0773
Sri Venkateswara Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epidermis is largely composed of keratinocytes (KCs), and the proliferation and differentiation of KCs from the stratum basale to the stratum corneum is the cellular hierarchy present in the epidermis. In this study, we explore the differentiation abilities of human hematopoietic stem cells (HSCs) into KCs. Cultured HSCs positive for CD34, CD45, and CD133 with prominent telomerase activity were induced with keratinocyte differentiation medium (KDM), which is composed of bovine pituitary extract (BPE), epidermal growth factor (EGF), insulin, hydrocortisone, epinephrine, transferrin, calcium chloride (CaCl

Indexed as

TelomeraseAnimalsCell DifferentiationCells, CulturedEpidermal CellsEpidermisHematopoietic Stem CellsHumansKeratinocytesKeratinsKeratinsTelomeraseFilaggrinHematopoietic stem cellsInvolucrinKeratin 10Keratin 14Keratinocytes

Identifiers

PMID38502372
OpenAlexW4392951392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.