Evidence map›Paper›PMID 38501945›Full record

ArticleChild neuropsychology : a journal on normal and abnormal development in childhood and adolescence2025

White matter tract integrity in isolated oral clefts: relationship to cognition and reading skills.

Jon Willie Goodwin, Lauren Hopkins, Amy Lynn Conrad

Abstract read
In one paragraph

Article in Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jon Willie GoodwinDepartment of Counseling, Clinical and School Psychology, University of California Santa Barbara, Santa Barbara, CA, USA.ORCID 0000-0002-1830-3195
Lauren HopkinsDepartment of Psychiatry, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA.
Amy Lynn ConradStead Family Department of Pediatrics, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA.ORCID 0000-0001-5360-7517

Funding

The University of Iowa Clinical and Translational Science AwardUL1TR002537 · NCATS · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, WINOKUR, PATRICIA · 2018 to 2022
$20.0M
University of Iowa Hawkeye Intellectual and Developmental Disabilities Research Center (Hawk-IDDRC)P50HD103556 · NICHD · UNIVERSITY OF IOWA · PI EDWIN TED G. ABEL, Lane Strathearn · 2021 to 2026
$8.5M
Brain Structure/Function in Children with Oral CleftsR01DE014399 · NIDCR · UNIVERSITY OF IOWA · PI NOPOULOS, PEGGY C · 2002 to 2012
$4.9M
University of Iowa - Research 3T MRI Connectome UpgradeS10OD025025 · OD · UNIVERSITY OF IOWA · PI MAGNOTTA, VINCENT A · 2018 to 2018
$1.9M
Training in Neuroimaging of Cognitive Development in Craniofacial DiagnosesK23DE024511 · NIDCR · UNIVERSITY OF IOWA · PI CONRAD, AMY LYNN · 2014 to 2018
$477k
NCATS NIH HHS UL1 TR002537NICHD NIH HHS P50 HD103556NIDCR NIH HHS K23 DE024511NIDCR NIH HHS R01 DE014399NIH HHS S10 OD025025
6 · The paper itself

Abstract

Children with isolated cleft of the lip and/or palate (iCL/P) have been shown to be at risk for impaired reading ability. Structural and functional neuroimaging studies have revealed subtle morphological and functional abnormalities correlated to cognition and reading ability. However, the integrity of white matter tracts and their potential relationship to reading performance in iCL/P is under-studied. The purpose of the present study was to evaluate white matter integrity related to cognition and reading skills among participants with and without iCL/P. Data from two cross-sectional, case/control studies with similar neuropsychological batteries and diffusion tensor imaging (DTI) protocols were combined. The final sample included 210 participants (ages 7 to 27 years). Group and sex differences in fractional anisotropy (FA) values were examined between participants with (

Indexed as

Cleft LipCleft PalateCognitionReadingWhite MatterAdolescentAdultAnisotropyCase-Control StudiesChildCross-Sectional StudiesDiffusion Tensor ImagingDyslexiaFemaleHumansMaleneuroimagingneuropsychologyOral cleftsreadingwhite matter tracts

Identifiers

PMID38501945
PMCPMC11411015

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.