Evidence map›Paper›PMID 38501869›Full record

ArticlemBio2024

Echinocandin persistence directly impacts the evolution of resistance and survival of the pathogenic fungus

Amir Arastehfar, Farnaz Daneshnia, Daniel J Floyd, Nathan Elias Jeffries, Mostafa Salehi, David S Perlin, Macit Ilkit, Cornelia Lass-Flöerl, Michael K Mansour

Open access · goldAbstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 10 citations in OpenAlex.

  1. Alkylamidobetaines Induced Changes in Multidrug-Resistant, BiofilmingInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Recent Outbreaks, Resistance Trends, and Control Measures inJournal of fungi (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Profound cell wall remodeling inMicrobiology spectrum · 2026
    Article
  6. Advancing the Understanding of the Mo-CBPProbiotics and antimicrobial proteins · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Tn-seq screens inmSphere · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Amir Arastehfar *Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-4361-4841
Farnaz Daneshnia *Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Daniel J FloydDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Nathan Elias JeffriesCenter for Regenerative Medicine, Boston, Massachusetts, USA.
Mostafa SalehiDepartment Industrial Engineering Faculty of K.N., Toosi University of Technology, Tehran, Iran.
David S PerlinCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.ORCID 0000-0002-1268-5524
Macit IlkitDivision of Mycology, Faculty of Medicine, University of Çukurova, Adana, Türkiye.ORCID 0000-0002-1174-4182
Cornelia Lass-FlöerlMedical University Innsbruck, Institute of Hygiene and Medical Microbiology, Innsbruck, Austria.
Michael K MansourDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-8892-8695
Harvard University · USMassachusetts General Hospital · USCukurova University · TRGeorgetown University · USInnsbruck Medical University · ATK.N.Toosi University of Technology · IR

Funding

The role of spleen tyrosine kinase (syk) in neutrophil responses to pathogenic fungi.R01AI132638 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MANSOUR, MICHAEL K · 2018 to 2021
$1.6M
NIAID NIH HHS R01 AI132638
6 · The paper itself

Abstract

Recent epidemiological studies documented an alarming increase in the prevalence of echinocandin-resistant (ECR) IMPORTANCE:

Indexed as

Candida glabrataEchinocandinsAnti-Bacterial AgentsAntifungal AgentsDrug Resistance, FungalMicafunginMicrobial Sensitivity TestsAnti-Bacterial AgentsAntifungal AgentsEchinocandinsMicafunginCandida glabrataechinocandinex vivoin vivopersistencetolerance

Identifiers

PMID38501869
PMCPMC11005346
OpenAlexW4392953172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.