Evidence map›Paper›PMID 38501663›Full record

ArticleJournal of virology2024

Functional dissection of the spike glycoprotein S1 subunit and identification of cellular cofactors for regulation of swine acute diarrhea syndrome coronavirus entry.

Yong-Le Yang, Bin Wang, Wentao Li, Hou-Li Cai, Qian-Yu Qian, Yu Qin, Fang-Shu Shi, Berend-Jan Bosch, Yao-Wei Huang

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Cell entry mechanisms of porcine enteric coronaviruses.The Journal of biological chemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Yong-Le Yang *Xianghu Laboratory, Hangzhou, China.
Bin Wang *State Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou, China.
Wentao Li *Virology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.ORCID 0000-0002-7114-762X
Hou-Li CaiDepartment of Veterinary Medicine, Zhejiang University, Hangzhou, China.
Qian-Yu QianCollege of Life Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Yu QinDepartment of Veterinary Medicine, Zhejiang University, Hangzhou, China.
Fang-Shu ShiDepartment of Veterinary Medicine, Zhejiang University, Hangzhou, China.
Berend-Jan BoschVirology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.ORCID 0000-0002-3864-232X
Yao-Wei HuangState Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou, China.ORCID 0000-0001-9755-8411
South China Agricultural University · CNZhejiang University · CNUtrecht University · NLZhejiang Chinese Medical University · CN

Funding

MOST | National Key Research and Development Program of China (NKPs) 2021YFD1801103
6 · The paper itself

Abstract

Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a novel porcine enteric coronavirus, and the broad interspecies infection of SADS-CoV poses a potential threat to human health. This study provides experimental evidence to dissect the roles of distinct domains within the SADS-CoV spike S1 subunit in cellular entry. Specifically, we expressed the S1 and its subdomains, S1

Indexed as

AlphacoronavirusCoronavirus InfectionsSpike Glycoprotein, CoronavirusAnimalsHeparan SulfateHumansMiceN-Acetylneuraminic AcidPeptide HydrolasesSwineHeparan SulfateN-Acetylneuraminic AcidPeptide HydrolasesSpike Glycoprotein, Coronavirusheparan sulfatereceptor-binding domain (RBD)sialic acidspikeswine acute diarrhea syndrome coronavirus (SADS-CoV)TMPRSS2

Identifiers

PMID38501663
PMCPMC11019839
OpenAlexW4392955403

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.