Evidence map›Paper›PMID 38501502›Full record

ArticleProtein science : a publication of the Protein Society2024

Ca2+/CaM dependent protein kinase II (CaMKII)α and CaMKIIβ hub domains adopt distinct oligomeric states and stabilities.

Can Özden, Sara MacManus, Ruth Adafia, Alfred Samkutty, Ana P Torres-Ocampo, Scott C Garman, Margaret M Stratton

Open access · bronzeAbstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Can ÖzdenDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.ORCID 0000-0002-5673-878X
Sara MacManusDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.
Ruth AdafiaDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.
Alfred SamkuttyDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.
Ana P Torres-OcampoDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.
Scott C GarmanDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.
Margaret M StrattonDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.ORCID 0000-0003-2686-9022
University of Massachusetts Amherst · US

Funding

Chemistry-Biology Interface Predoctoral Training GrantT32GM139789 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ERIC Robert STRIETER · 2021 to 2026
$3.4M
Unraveling the molecular events driven by CaMKII in Ca2+-coupled cellsR35GM145376 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Margaret M Stratton · 2022 to 2026
$2.1M
NIGMS NIH HHS R35 GM145376NIGMS NIH HHS T32 GM139789
6 · The paper itself

Abstract

Ca

Indexed as

CalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2HumansMaleSemenCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CaMKIIoligomerization domainprotein foldingstoichiometry

Identifiers

PMID38501502
PMCPMC10962473
OpenAlexW4392956207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.