Evidence map›Paper›PMID 38501427›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2024

[Modulating gut microbiota improves neurological function and depressive symptoms in rats with post-stroke depression].

X Li, Y Liu, K Deng, Y Hu

Abstract readEnglish Abstract
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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  3. Article
  4. [Therapeutic effects of inulin-type oligosaccharides ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

X LiWuhan Wuchang Hospital/Wuhan University of Science and Technology Affiliated Wuchang Hospital, Wuhan 430061, China.
Y LiuWuhan Wuchang Hospital/Wuhan University of Science and Technology Affiliated Wuchang Hospital, Wuhan 430061, China.
K DengWuhan Wuchang Hospital/Wuhan University of Science and Technology Affiliated Wuchang Hospital, Wuhan 430061, China.
Y HuWuhan Wuchang Hospital/Wuhan University of Science and Technology Affiliated Wuchang Hospital, Wuhan 430061, China.
Wuchang University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of modulating gut microbiota for improving brain injury in rats with post-stroke depression.

methodsAdult SD rats were randomized into normal control, middle cerebral artery occlusion (MCAO), post-stroke depression (PSD), PSD with fecal transplantation, PSD with antibiotics (rifaximin), PSD with probiotics (lactobacilli), and PSD with fluoxetine treatment groups (

resultsCompared with those in the control group, the rats in MCAO and PSD groups had significantly increased neurological function scores, TMAO level, the ratio of TMAO/H

conclusionIn PSD rats, TMAO/H

Indexed as

DepressionGastrointestinal MicrobiomeMethylaminesAnimalsAnti-Bacterial AgentsFluoxetineImmunoglobulin GOccludinRatsRats, Sprague-DawleySugarsWaterAnti-Bacterial AgentsFluoxetineImmunoglobulin GMethylaminesOccludinSugarstrimethyloxamineWaterblood-brain barrierintestinal florapost-stroke depressionTMAO/H2S

Identifiers

PMID38501427
PMCPMC10954514
OpenAlexW4394759602

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.