Evidence map›Paper›PMID 38500958›Full record

ArticleLancet regional health. Americas2024

Excess tuberculosis risk during and following incarceration in Paraguay: a retrospective cohort study.

Guillermo Sequera, Gladys Estigarribia-Sanabria, Sarita Aguirre, Claudia Piñanez, Leonardo Martinez, Rafael Lopez-Olarte, Jason R Andrews, Katharine S Walter, Julio Croda, Alberto L Garcia-Basteiro

Open access · goldAbstract read
In one paragraph

Article in Lancet regional health. Americas, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 12 citations in OpenAlex.

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  9. Transmission ofEpidemiology and infection · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 5 countries.

Guillermo SequeraCátedra de Salud Pública, Universidad Nacional de Asunción (UNA), Paraguay.
Gladys Estigarribia-SanabriaInstituto Regional de Investigación en Salud, Universidad Nacional de Caaguazú- (UNCA), Coronel Oviedo, Paraguay.
Sarita AguirrePrograma Nacional de Control de la Tuberculosis, Asunción, Paraguay.
Claudia PiñanezDepartamento de Sanidad Penitenciaria, Ministerio de Justicia, Paraguay.
Leonardo MartinezDepartment of Epidemiology, School of Public Health, Boston University, Boston, MA, USA.
Rafael Lopez-OlarteFormer Regional Tuberculosis Adviser, Pan American Health Organization, Washington, DC, USA.
Jason R AndrewsDivision of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Katharine S WalterDivision of Epidemiology, University of Utah, Salt Lake City, UT, USA.
Julio CrodaDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Alberto L Garcia-BasteiroISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Universidade Federal de Mato Grosso do Sul · BRBarcelona Institute for Global Health · ESBoston University · USCentro de Investigación Biomédica en Red · ESMinisterio de Salud Pública y Bienestar Social · PYStanford University · USUniversity of Utah · USWorld Health Organization Regional Office for the Americas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The increased risk of tuberculosis (TB) among people deprived of liberty (PDL) is due to individual and institution-level factors. We followed a cohort of PDL from 5 prisons in Paraguay to describe the risk of TB during incarceration and after they were released. Methods: We linked a 2013 national census of prisons with TB records from the TB Program from 2010 to 2021 to identify TB notifications among incarcerated and formerly incarcerated individuals. We used multivariable Cox regression models to quantify the risk of TB during and following incarceration and to identify risk factors associated with TB. Findings: Among 2996 individuals incarcerated, 451 (15.1%) were diagnosed with TB. Of these, 262 (58.1%) cases occurred during incarceration and 189 (41.9%) occurred in the community after release. In prison, the hazard ratio of developing TB was 1.97 (95% CI: 1.52-2.61) after six months of incarceration and increased to 2.78 (95% CI: 1.82-4.24) after 36 months compared with the first six months. The overall TB notification rate was 2940 per 100,000 person-years. This rate increased with the duration of incarceration from 1335 per 100,000 person-years in the first year to 8455 per 100,000 person-years after 8 years. Among former prisoners, the rate of TB decreased from 1717 in the first year after release to 593 per 100 000 person-years after 8 years of follow up. Interpretation: Our study shows the alarming risk of TB associated with prison environments in Paraguay, and how this risk persists for years following incarceration. Effective TB control measures to protect the health of people during and following incarceration are urgently needed. Funding: Paraguay National Commission of Science and Technology grant CONACYT PIN 15-705 (GS, GES, SA).

Indexed as

EpidemiologyParaguayPrisonsTransmissionTuberculosis

Identifiers

PMID38500958
PMCPMC10945421
OpenAlexW4390815449

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.