Evidence map›Paper›PMID 38500844›Full record

ArticleAdvances in hematology2024

The Association of Anticoagulation Intensity with Outcomes in Hospitalized COVID-19 Patients.

Rena Zheng, Alexandra Solomon, Madeline DiLorenzo, Iniya Rajendran, Joseph Park, Vrushali Dhongade, Michael A Garcia, Robert T Eberhardt, John Mark Sloan, Janice Weinberg and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advances in hematology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Rena ZhengUMass Chan Medical School, UMass Medical Center, Department of Medicine, Division of Hematology-Oncology, Worcester, MA, USA.ORCID https://orcid.org/0009-0008-5284-3444
Alexandra SolomonEastern Vascular Associates, Denville, NJ, USA.ORCID https://orcid.org/0000-0003-2363-886X
Madeline DiLorenzoNew York University Grossman School of Medicine, Department of Medicine, Division of Infectious Diseases and Immunology, New York, NY, USA.ORCID https://orcid.org/0000-0003-1284-6428
Iniya RajendranUniversity of Arizona, College of Medicine, Department of Medicine, Division of Cardiology, Tucson, AZ, USA.
Joseph ParkBrigham and Women's Hospital, Department of Medicine, Boston, MA, USA.ORCID https://orcid.org/0000-0001-5757-0344
Vrushali DhongadeBrigham and Women's Hospital, Department of Neurology, Boston, MA, USA.ORCID https://orcid.org/0009-0004-2210-3040
Michael A GarciaValley Medical Center Pulmonary & Sleep Disorder Clinic, Covington, WA, USA.
Robert T EberhardtBoston University Chobanian & Avedisian School of Medicine, Boston Medical Center, Department of Medicine, Section of Cardiovascular Medicine, Boston, MA, USA.ORCID https://orcid.org/0000-0002-5076-7416
John Mark SloanBoston University Chobanian & Avedisian School of Medicine, Boston Medical Center, Department of Medicine, Section of Hematology & Medical Oncology, Boston, MA, USA.ORCID https://orcid.org/0000-0001-7069-4528
Janice WeinbergBoston University School of Public Health, Department of Biostatistics, Boston, MA, USA.ORCID https://orcid.org/0000-0002-3503-0061
Elizabeth S KlingsBoston University Chobanian & Avedisian School of Medicine, Boston Medical Center, Department of Medicine, The Pulmonary Center, Boston, MA, USA.ORCID https://orcid.org/0000-0003-4879-720X
Boston University · USBrigham and Women's Hospital · USNew York University · USUniversity of Arizona · USUniversity of Massachusetts Chan Medical School · USValley Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venous thromboembolism (VTE) risk is increased in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A key question was whether increased intensity of anticoagulation would help prevent VTE and improve patient outcomes, including transfer to the intensive care unit (ICU) and mortality. At the start of the coronavirus disease-19 (COVID-19) pandemic, our institution, Boston Medical Center, instituted a VTE risk stratification protocol based on patients' initial D-dimer levels, medical history, and presence of thrombosis to determine whether they should receive standard-dose prophylaxis, high-dose prophylaxis, or therapeutic anticoagulation. We performed a retrospective observational cohort study examining the association of degree of anticoagulation with outcomes in 915 hospitalized COVID-19 patients hospitalized initially on the general inpatient wards between March 1,

Identifiers

PMID38500844
PMCPMC10948223
OpenAlexW4392637093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.