Evidence map›Paper›PMID 38500745›Full record

ArticleAmerican journal of nuclear medicine and molecular imaging2024

Poly(ADP-ribose) polymerase (PARP)-targeted PET imaging in non-oncology application: a pilot study in preclinical models of nonalcoholic steatohepatitis.

Troels E Jeppesen, Tuo Shao, Jiahui Chen, Jimmy S Patel, Xin Zhou, Andreas Kjaer, Steven H Liang

Open access · bronzeAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of nuclear medicine and molecular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Troels E JeppesenDivision of Nuclear Medicine, Department of Radiology, Harvard Medical School and Massachusetts General Hospital Boston, MA, USA.
Tuo ShaoDivision of Nuclear Medicine, Department of Radiology, Harvard Medical School and Massachusetts General Hospital Boston, MA, USA.
Jiahui ChenDivision of Nuclear Medicine, Department of Radiology, Harvard Medical School and Massachusetts General Hospital Boston, MA, USA.
Jimmy S PatelDepartment of Radiology and Imaging Sciences, Emory University Atlanta, GA, USA.
Xin ZhouDepartment of Radiology and Imaging Sciences, Emory University Atlanta, GA, USA.
Andreas KjaerDepartment of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet Copenhagen, Denmark.
Steven H LiangDivision of Nuclear Medicine, Department of Radiology, Harvard Medical School and Massachusetts General Hospital Boston, MA, USA.
University of Copenhagen · DK

Funding

T32 Training Program in Cancer BiologyT32CA275777 · NCI · EMORY UNIVERSITY · PI David Sung-wen Yu · 2023 to 2026
$1.1M
NCI NIH HHS T32 CA275777
6 · The paper itself

Abstract

Poly(ADP-ribose) polymerase (PARP) activation often indicates a disruptive signal to lipid metabolism, the physiological alteration of which may be implicated in the development of non-alcoholic fatty liver disease. The objective of this study was to evaluate the capability of [

Indexed as

Gallium 68non-alcoholic steatohepatitispoly(ADP-ribose) polymerase (PARP)Positron emission tomography (PET)

Identifiers

PMID38500745
PMCPMC10944370
OpenAlexW4394738520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.