Evidence map›Paper›PMID 38500738›Full record

ArticlePulmonary circulation2024

Plasma NEDD9 is increased following SARS-CoV-2 infection and associates with indices of pulmonary vascular dysfunction.

George A Alba, Iris Y Zhou, Molly Mascia, Michael Magaletta, Jehan W Alladina, Francesca L Giacona, Leo C Ginns, Peter Caravan, Bradley A Maron, Sydney B Montesi

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

George A AlbaHarvard Medical School Boston Massachusetts USA.ORCID 0000-0002-6876-7836
Iris Y ZhouHarvard Medical School Boston Massachusetts USA.
Molly MasciaHarvard Medical School Boston Massachusetts USA.
Michael MagalettaDepartment of Radiology, Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital Boston Massachusetts USA.
Jehan W AlladinaHarvard Medical School Boston Massachusetts USA.
Francesca L GiaconaDivision of Pulmonary and Critical Care Medicine Massachusetts General Hospital Boston Massachusetts USA.
Leo C GinnsHarvard Medical School Boston Massachusetts USA.
Peter CaravanHarvard Medical School Boston Massachusetts USA.
Bradley A MaronDivision of Cardiovascular Medicine Brigham and Women's Hospital Boston Massachusetts USA.
Sydney B MontesiHarvard Medical School Boston Massachusetts USA.
Harvard University · USMassachusetts General Hospital · USUniversity of Maryland, Baltimore · US

Funding

PET-MR Imaging of pulmonary fibrosisR01HL153606 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI CARAVAN, PETER D, CATANA, CIPRIAN · 2021 to 2025
$4.1M
Vascular Leak and Outcomes in IPFK23HL150331 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MONTESI, SYDNEY · 2020 to 2024
$887k
Quantitative MRI-PET Imaging of Pulmonary FibrosisK25HL148837 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ZHOU, IRIS YUWEN · 2020 to 2023
$686k
NHLBI NIH HHS K23 HL150331NHLBI NIH HHS K25 HL148837NHLBI NIH HHS R01 HL153606
6 · The paper itself

Abstract

Compared to healthy volunteers, participants with post-acute sequelae of SARS-CoV-2 infection (PASC) demonstrated increased plasma levels of the prothrombotic protein NEDD9, which associated inversely with indices of pulmonary vascular function. This suggests persistent pulmonary vascular dysfunction may play a role in the pathobiology of PASC.

Indexed as

NEDD9post‐acute sequelae of SARS‐CoV‐2 infectionpulmonary vascular dysfunction

Identifiers

PMID38500738
PMCPMC10946282
OpenAlexW4392917418

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.