Evidence map›Paper›PMID 38500732›Full record

ArticleFrontiers in public health2024

Determinants of HIV late presentation among men who have sex with men in Portugal (2014-2019): who's being left behind?

Ricardo Abrantes, Victor Pimentel, Mafalda N S Miranda, Ana Rita Silva, António Diniz, Bianca Ascenção, Carmela Piñeiro, Carmo Koch, Catarina Rodrigues, Cátia Caldas and 48 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

58 authors at 19 institutions in 1 country.

Ricardo Abrantes *Global Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Institute of Hygiene and Tropical Medicine, NOVA University of Lisbon (IHMT/UNL), Lisbon, Portugal.
Victor Pimentel *Global Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Institute of Hygiene and Tropical Medicine, NOVA University of Lisbon (IHMT/UNL), Lisbon, Portugal.
Mafalda N S MirandaGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Institute of Hygiene and Tropical Medicine, NOVA University of Lisbon (IHMT/UNL), Lisbon, Portugal.
Ana Rita SilvaServiço de Infeciologia, Hospital Beatriz Ângelo, Loures, Portugal.
António DinizU. Imunodeficiência, Hospital Pulido Valente, Centro Hospitalar Universitário de Lisboa Norte, Lisbon, Portugal.
Bianca AscençãoServiço de Infeciologia, Centro Hospitalar de Setúbal, Setúbal, Portugal.
Carmela PiñeiroServiço de Doenças Infeciosas, Centro Hospitalar Universitário de São João, Porto, Portugal.
Carmo KochCentro de Biologia Molecular, Serviço de Imunohemoterapia do Centro Hospitalar Universitário de São João, Porto, Portugal.
Catarina RodriguesServiço de Medicina 1.4, Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Cátia CaldasServiço de Doenças Infeciosas, Centro Hospitalar Universitário de São João, Porto, Portugal.
Célia MoraisServiço de Patologia Clínica, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Domitília FariaServiço de Medicina 3, Hospital de Portimão, Centro Hospitalar Universitário do Algarve, Portimão, Portugal.
Elisabete Gomes da SilvaUnidade Local de Saúde do Baixo Alentejo, Hospital José Joaquim Fernandes, Beja, Portugal.
Eugénio TeófiloServiço de Medicina 2.3, Hospital de Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.
Fátima MonteiroCentro de Biologia Molecular, Serviço de Imunohemoterapia do Centro Hospitalar Universitário de São João, Porto, Portugal.
Fausto RoxoHospital de Dia de Doenças Infeciosas, Hospital Distrital de Santarém, Santarém, Portugal.
Fernando MaltezServiço de Doenças Infeciosas, Hospital Curry Cabral, Centro Hospitalar de Lisboa, Lisbon, Portugal.
Fernando RodriguesServiço de Patologia Clínica, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Guilhermina GaiãoServiço de Patologia Clínica, Hospital de Sta Maria, Centro Hospitalar Universitário de Lisboa Norte, Lisbon, Portugal.
Helena RamosServiço de Patologia Clínica, Centro Hospitalar do Porto, Porto, Portugal.
Inês CostaLaboratório de Biologia Molecular (LMCBM, SPC, CHLO-HEM), Lisbon, Portugal.
Isabel GermanoServiço de Medicina 1.4, Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Joana SimõesServiço de Medicina 1.4, Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Joaquim OliveiraServiço de Infeciologia, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
José FerreiraServiço de Medicina 2, Hospital de Faro, Centro Hospitalar Universitário do Algarve, Faro, Portugal.
José PoçasServiço de Infeciologia, Centro Hospitalar de Setúbal, Setúbal, Portugal.
José Saraiva da CunhaServiço de Infeciologia, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Jorge SoaresServiço de Doenças Infeciosas, Centro Hospitalar Universitário de São João, Porto, Portugal.
Sandra FernandesLaboratório de Biologia Molecular (LMCBM, SPC, CHLO-HEM), Lisbon, Portugal.
Kamal MansinhoServiço de Doenças Infeciosas, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal.
Liliana PedroServiço de Medicina 3, Hospital de Portimão, Centro Hospitalar Universitário do Algarve, Portimão, Portugal.
Maria João AleixoServiço de Infeciologia, Hospital Garcia da Orta, Almada, Portugal.
Maria João GonçalvesServiço de Infeciologia, Centro Hospitalar do Porto, Porto, Portugal.
Maria José ManataServiço de Doenças Infeciosas, Hospital Curry Cabral, Centro Hospitalar de Lisboa, Lisbon, Portugal.
Margarida MouroServiço de Infeciologia, Hospital de Aveiro, Centro Hospitalar Baixo Vouga, Aveiro, Portugal.
Margarida SerradoU. Imunodeficiência, Hospital Pulido Valente, Centro Hospitalar Universitário de Lisboa Norte, Lisbon, Portugal.
Micaela CaixeiroServiço de Infeciologia, Hospital Dr. Fernando da Fonseca, Amadora, Portugal.
Nuno MarquesServiço de Infeciologia, Hospital Garcia da Orta, Almada, Portugal.
Olga CostaServiço de Patologia Clínica, Biologia Molecular, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Patrícia PachecoServiço de Infeciologia, Hospital Dr. Fernando da Fonseca, Amadora, Portugal.
Paula ProençaServiço de Infeciologia, Hospital de Faro, Centro Hospitalar Universitário do Algarve, Faro, Portugal.
Paulo RodriguesServiço de Infeciologia, Hospital Beatriz Ângelo, Loures, Portugal.
Raquel PinhoServiço de Medicina 3, Hospital de Portimão, Centro Hospitalar Universitário do Algarve, Portimão, Portugal.
Raquel TavaresServiço de Infeciologia, Hospital Beatriz Ângelo, Loures, Portugal.
Ricardo Correia de AbreuServiço de Infeciologia, Unidade de Local de Saúde de Matosinhos, Hospital Pedro Hispano, Matosinhos, Portugal.
Rita Côrte-RealServiço de Patologia Clínica, Biologia Molecular, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Rosário SerrãoServiço de Doenças Infeciosas, Centro Hospitalar Universitário de São João, Porto, Portugal.
Rui Sarmento E CastroServiço de Infeciologia, Centro Hospitalar do Porto, Porto, Portugal.
Sofia NunesServiço de Infeciologia, Hospital de Aveiro, Centro Hospitalar Baixo Vouga, Aveiro, Portugal.
Telo FariaUnidade Local de Saúde do Baixo Alentejo, Hospital José Joaquim Fernandes, Beja, Portugal.
Teresa BaptistaServiço de Doenças Infeciosas, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal.
Daniel SimõesGrupo de Ativistas em Tratamentos (GAT), Lisbon, Portugal.
Luis MendãoGrupo de Ativistas em Tratamentos (GAT), Lisbon, Portugal.
M Rosário O MartinsGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Institute of Hygiene and Tropical Medicine, NOVA University of Lisbon (IHMT/UNL), Lisbon, Portugal.
Perpétua GomesLaboratório de Biologia Molecular (LMCBM, SPC, CHLO-HEM), Lisbon, Portugal.
Marta Pingarilho *Global Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Institute of Hygiene and Tropical Medicine, NOVA University of Lisbon (IHMT/UNL), Lisbon, Portugal.
Ana B Abecasis *Global Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Institute of Hygiene and Tropical Medicine, NOVA University of Lisbon (IHMT/UNL), Lisbon, Portugal.
BESTHOPE Study Group
Hospital de São João · PTUniversity of Lisbon · PTAlgarve Biomedical Center · PTCentro Hospitalar do Baixo Vouga · PTHospitais da Universidade de Coimbra · PTCentro Hospitalar do Porto · PTHospital Beatriz Ângelo · PTHospital de São José · PTCentro Hospitalar de Lisboa Central · PTHospital Curry Cabral · PTHospital de Egas Moniz · PTHospital de São Bernardo · PTHospital Garcia de Orta · PTHospital Prof. Dr. Fernando Fonseca · PTHospital Pulido Valente · PTEscola Superior de Saúde Egas Moniz · PTHospital de Santo António · PTHospital Pedro Hispano · PTInstituto Politécnico de Santarém · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: HIV late presentation (LP) remains excessive in Europe. We aimed to analyze the factors associated with late presentation in the MSM population newly diagnosed with HIV in Portugal between 2014 and 2019. Methods: We included 391 newly HIV-1 diagnosed Men who have Sex with Men (MSM), from the BESTHOPE project, in 17 countrywide Portuguese hospitals. The data included clinical and socio-behavioral questionnaires and the viral genomic sequence obtained in the drug resistance test before starting antiretrovirals (ARVs). HIV-1 subtypes and epidemiological surveillance mutations were determined using different bioinformatics tools. Logistic regression was used to estimate the association between predictor variables and late presentation (LP). Results: The median age was 31 years, 51% had a current income between 501-1,000 euros, 28% were migrants. 21% had never been tested for HIV before diagnosis, with 42.3% of MSM presenting LP. 60% were infected with subtype B strains. In the multivariate regression, increased age at diagnosis, higher income, lower frequency of screening, STI ever diagnosed and higher viral load were associated with LP. Conclusion: Our study suggests that specific subgroups of the MSM population, such older MSM, with higher income and lower HIV testing frequency, are not being targeted by community and clinical screening services. Overall, targeted public health measures should be strengthened toward these subgroups, through strengthened primary care testing, expanded access to PrEP, information and promotion of HIV self-testing and more inclusive and accessible health services.

Indexed as

HIV InfectionsSexual and Gender MinoritiesAdultEuropeHomosexuality, MaleHumansMalePortugaldrug resistanceHIV-1late presentationmen who have sex with menPortugalvulnerable populations

Identifiers

PMID38500732
PMCPMC10947991
OpenAlexW4392292676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.