Evidence map›Paper›PMID 38500653›Full record

ArticleInfectious microbes & diseases2020

Azithromycin Exerts Bactericidal Activity and Enhances Innate Immune Mediated Killing of MDR

Erlinda R Ulloa, Armin Kousha, Hannah Tsunemoto, Joe Pogliano, Carmelo Licitra, John J LiPuma, George Sakoulas, Victor Nizet, Monika Kumaraswamy

Open access · goldAbstract read
In one paragraph

Article in Infectious microbes & diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Extended-Spectrum β-Lactamase-ProducingAntibiotics (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Evaluation of the Whole Proteome ofFrontiers in medicine · 2021
    Article
  13. Antimicrobial agents and chemotherapy · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Erlinda R UlloaCollaborative to Halt Antibiotic-Resistant Microbes (CHARM), University of California San Diego, La Jolla, CA 92093, USA.
Armin KoushaDepartment of Pediatrics, University of California San Diego, La Jolla, CA 92093, USA.
Hannah TsunemotoDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Joe PoglianoCollaborative to Halt Antibiotic-Resistant Microbes (CHARM), University of California San Diego, La Jolla, CA 92093, USA.
Carmelo LicitraInfectious Diseases, Orlando Health Medical Group, Orlando, FL 32806, USA.
John J LiPumaDepartment of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA.
George SakoulasCollaborative to Halt Antibiotic-Resistant Microbes (CHARM), University of California San Diego, La Jolla, CA 92093, USA.
Victor NizetCollaborative to Halt Antibiotic-Resistant Microbes (CHARM), University of California San Diego, La Jolla, CA 92093, USA.
Monika KumaraswamyCollaborative to Halt Antibiotic-Resistant Microbes (CHARM), University of California San Diego, La Jolla, CA 92093, USA.
University of California, San Diego · USChildren's Hospital of Philadelphia · USNorwegian University of Life Sciences · NOOrlando Health · USUniversity of Michigan–Ann Arbor · US

Funding

Pediatric Scientist Development Program (PSDP) [K12]K12HD000850 · NICHD · YALE UNIVERSITY · PI Sallie R. Permar · 1987 to 2026
$44.1M
UC San Diego Clinical and Translational Research InstituteKL2TR001444 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2015 to 2024
$15.4M
Systems Biology Approach to Redefine Susceptibility Testing and Treatment of MDR Pathogens in the Context of Host ImmunityU01AI124316 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PALSSON, BERNHARD O · 2016 to 2020
$10.2M
Safety and Dose Optimization of High-Dose Anakinra in Kawasaki DiseaseU54HD090259 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIGAM, SANJAY K · 2016 to 2018
$2.2M
Beta-Lactamase Inhibitors Sensitize Multidrug-Resistant Gram-negative Pathogens to Innate Immune ClearanceK08AI151253 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI ULLOA, ERLINDA ROSE · 2020 to 2024
$1.0M
NCATS NIH HHS KL2 TR001444NIAID NIH HHS K08 AI151253NIAID NIH HHS U01 AI124316NICHD NIH HHS K12 HD000850NICHD NIH HHS U54 HD090259
6 · The paper itself

Abstract

Azithromycin (AZM), the most commonly prescribed antibiotic in the United States, is thought to have no activity against multidrug-resistant Gram-negative pathogens such as

Indexed as

Achromobacter xylosoxidansantimicrobial susceptibility testingazithromycinhost defensemultidrug resistancetreatment

Identifiers

PMID38500653
PMCPMC10947418
OpenAlexW3018616900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.