Evidence map›Paper›PMID 38500602›Full record

ArticleFrontiers in veterinary science2024

A fusion protein of vimentin with Fc fragment inhibits Japanese encephalitis virus replication.

Taoping Zhang, Zhixin Chen, Lyu Xie, Ruixian Xu, Lu Chen, Ting Jia, Wengang Shi, Yongbo Wang, Yuzhu Song, Qinqin Han and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Vimentin Dynamics in Viral Infection: Shield or Sabotage?International journal of molecular sciences · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Taoping Zhang *Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Zhixin Chen *Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Lyu Xie *Institute of Basic Medical Sciences, School of Basic Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Ruixian XuFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Lu ChenFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Ting JiaFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Wengang ShiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Yongbo WangDepartment of Clinical Laboratory, The First People's Hospital of Yunnan Province, Kunming, China.
Yuzhu SongFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Qinqin HanFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Xueshan XiaFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Tao YuanYunnan Provincial Key Laboratory of Clinical Virology, The First People's Hospital of Yunnan Province, Kunming, China.
Jinyang ZhangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Kunming University of Science and Technology · CNFirst People's Hospital of Yunnan Province · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNYunnan Center for Disease Control And Prevention · CNYunnan Provincial Infectious Disease Hospital · CN

Funding

NIA NIH HHS N01 AG050003
6 · The paper itself

Abstract

Japanese encephalitis virus (JEV), a member of the Flaviviridae family and a flavivirus, is known to induce acute encephalitis. Vimentin protein has been identified as a potential receptor for JEV, engaging in interactions with the viral membrane protein. The Fc fragment, an integral constituent of immunoglobulins, plays a crucial role in antigen recognition by dendritic cells (DCs) or phagocytes, leading to subsequent antigen presentation, cytotoxicity, or phagocytosis. In this study, we fused the receptor of JEV vimentin with the Fc fragment of IgG and expressed the resulting vimentin-Fc fusion protein in

Indexed as

antiviralFc fragmentfusion proteinJEVvimentin

Identifiers

PMID38500602
PMCPMC10944967
OpenAlexW4392371750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.