Evidence map›Paper›PMID 38500566›Full record

ArticlePain reports2024

Virtually delivered Mindfulness-Oriented Recovery Enhancement (MORE) reduces daily pain intensity in patients with lumbosacral radiculopathy: a randomized controlled trial.

Ryan S Wexler, Devon J Fox, Danielle ZuZero, Melissa Bollen, Anand Parikshak, Hannah Edmond, Johnny Lemau, Diane Montenegro, Jillian Ramirez, Sophia Kwin and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pain reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Ryan S WexlerHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.ORCID https://orcid.org/0000-0003-0121-2323
Devon J FoxHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Danielle ZuZeroHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Melissa BollenHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Anand ParikshakHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Hannah EdmondHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Johnny LemauHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Diane MontenegroHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Jillian RamirezHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Sophia KwinHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Austin R ThompsonDepartment of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, OR, USA.
Hans L CarlsonDepartment of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, OR, USA.
Lynn M MarshallDepartment of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, OR, USA.
Thomas KernDepartment of Anesthesiology and Perioperative Medicine, Oregon Health & Science University, Portland, OR, USA.
Scott D MistDepartment of Anesthesiology and Perioperative Medicine, Oregon Health & Science University, Portland, OR, USA.
Ryan BradleyHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Douglas A HanesHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Heather ZwickeyHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Courtney K PickworthHelfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
National University of Natural Medicine · USOregon Health & Science University · USCleveland Clinic · US

Funding

Mentorship in Clinical Complementary and Integrative Health ResearchK24AT011568 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BRADLEY, RYAN D · 2021 to 2025
$762k
NCCIH NIH HHS K24 AT011568
6 · The paper itself

Abstract

Introduction: Lumbosacral radiculopathy (LR), also known as sciatica, is a common type of radiating neurologic pain involving burning, tingling, and numbness in the lower extremities. It has an estimated lifetime prevalence as high as 43%. Objectives: The objective of this randomized controlled trial was to evaluate the impact of virtually delivered Mindfulness-Oriented Recovery Enhancement (MORE) on patients with LR during the COVID-19 pandemic. Methods: Potentially eligible patients were identified using electronic health record queries and phone screenings. Participants were then randomized to MORE or treatment-as-usual (TAU) for 8 weeks, with pain intensity assessed daily. At baseline and follow-up visits, participants completed questionnaires assessing the primary outcome, disability, as well as quality of life, depression, mindful reinterpretation of pain, and trait mindfulness. Results: In our study, patients undergoing virtual delivery of MORE had greater improvements in daily pain intensity ( Conclusion: Among patients with lumbar radiculopathy, MORE significantly reduced daily pain intensity but did not decrease disability or depression symptoms. Given the long duration of symptoms in our sample, we hypothesize the discrepancy between changes in daily pain intensity and disability is due to fear avoidance behaviors common in patients with chronic pain. As the first trial of a mindfulness intervention in patients with LR, these findings should inform future integrative approaches to LR treatment, particularly when considering the increasing use of virtual interventions throughout the COVID-19 pandemic.

Indexed as

Chronic low back painIntegrative pain managementLumbosacral radiculopathyMindfulness-based interventionsMindfulness-Oriented Recovery Enhancement

Identifiers

PMID38500566
PMCPMC10948133
OpenAlexW4393055894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.