Evidence map›Paper›PMID 38500484›Full record

ReviewFrontiers in neuroscience2024

The mechanistic effects of acupuncture in rodent neurodegenerative disease models: a literature review.

Boxuan Li, Shizhe Deng, Hailun Jiang, Weiming Zhu, Bifang Zhuo, Yuzheng Du, Zhihong Meng

Abstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The role of Foxo3a in neuron-mediated cognitive impairment.Frontiers in molecular neuroscience · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Boxuan Li *National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.
Shizhe Deng *National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.
Hailun JiangNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.
Weiming ZhuNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.
Bifang ZhuoNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.
Yuzheng DuNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.
Zhihong MengNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodegenerative diseases refer to a battery of medical conditions that affect the survival and function of neurons in the brain, which are mainly presented with progressive loss of cognitive and/or motor function. Acupuncture showed benign effects in improving neurological deficits, especially on movement and cognitive function impairment. Here, we reviewed the therapeutic mechanisms of acupuncture at the neural circuit level in movement and cognition disorders, summarizing the influence of acupuncture in the dopaminergic system, glutamatergic system, γ-amino butyric acid-ergic (GABAergic) system, serotonergic system, cholinergic system, and glial cells at the circuit and synaptic levels. These findings can provide targets for clinical treatment and perspectives for further studies.

Indexed as

acupuncturecognitive impairmentmovement disorderneural circuitneurodegenerative disease

Identifiers

PMID38500484
PMCPMC10944972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.