Evidence map›Paper›PMID 38500279›Full record

ReviewCurrent diabetes reviews2025

Herbal Nanoformulations for Diabetes: Mechanisms, Formulations, and Clinical Impact.

Sunita, Rahul Kaushik, Krishan Kumar Verma, Rehana Parveen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current diabetes reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

SunitaDepartment of Pharmacy, Metro College of Health Science and Research, Plot No.41, Knowledge Park-3, Greater Noida, Uttar Pradesh, India.
Rahul KaushikDepartment of Pharmacy, Metro College of Health Science and Research, Plot No.41, Knowledge Park-3, Greater Noida, Uttar Pradesh, India.ORCID 0000-0003-2223-5399
Krishan Kumar VermaDepartment of Pharmacy, Metro College of Health Science and Research, Plot No.41, Knowledge Park-3, Greater Noida, Uttar Pradesh, India.
Rehana ParveenDepartment of Pharmacy, Metro College of Health Science and Research, Plot No.41, Knowledge Park-3, Greater Noida, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus remains a global health challenge, demanding innovative therapeutic strategies. Herbal remedies have garnered attention for their potential in diabetes management, and recent advancements in nanotechnology have enabled the development of herbal nanoformulations with enhanced efficacy and bioavailability.

objectiveThis review aimed to comprehensively analyze the mechanisms, formulations, and clinical impact of herbal nanoformulations in managing diabetes mellitus.

methodA systematic literature search was conducted to identify relevant studies exploring the mechanisms of action, various formulations, and clinical outcomes of herbal nanoformulations in diabetes management.

resultHerbal nanoformulations exert their anti-diabetic effects through multiple mechanisms, including enhanced bioavailability, improved tissue targeting, and potentiation of insulin signaling pathways. Various herbal ingredients, such as bitter melon, fenugreek, and Gymnema sylvestre, have been encapsulated into nanocarriers, like liposomes, polymeric nanoparticles, and solid lipid nanoparticles, to enhance their therapeutic potential. Clinical studies have demonstrated promising results, showing improvements in glycemic control, lipid profile, and antioxidant status with minimal adverse effects.

conclusionHerbal nanoformulations represent a promising avenue for the management of diabetes mellitus, offering improved therapeutic outcomes compared to conventional herbal preparations. Further research is warranted to optimize formulation strategies, elucidate long-term safety profiles, and explore the potential synergistic effects of herbal nanoformulations in combination therapies for diabetes management.

Indexed as

Diabetes MellitusHypoglycemic AgentsNanoparticlesAnimalsBiological AvailabilityDrug CompoundingHumansPhytotherapyPlant PreparationsHypoglycemic AgentsPlant Preparationsclinical efficacy.diabetes mellitusHerbal nanoformulationsnanoparticlesnanosuspensionnanosystem

Identifiers

PMID38500279
OpenAlexW4392966330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.