Evidence map›Paper›PMID 38500232›Full record

ArticleJournal of medical case reports2024

Acalypha indica induced acute oxidative haemolysis and methaemoglobinaemia: two case reports.

Kusala Maddumabandara, Arun Rajaratnam, Mohamed Ishfak, Nimali Samarakoon, Kithmini Ellepola, Sunil Bowattage

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kusala MaddumabandaraNational Hospital Kandy, Kandy, Sri Lanka.
Arun RajaratnamNational Hospital Kandy, Kandy, Sri Lanka. nura321@hotmail.com.ORCID http://orcid.org/0000-0001-5849-8962
Mohamed IshfakNational Hospital Kandy, Kandy, Sri Lanka.
Nimali SamarakoonNational Hospital Kandy, Kandy, Sri Lanka.
Kithmini EllepolaNational Hospital Kandy, Kandy, Sri Lanka.
Sunil BowattageNational Hospital Kandy, Kandy, Sri Lanka.
Teaching Hospital Kandy · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHerbal products and traditional remedies are commonly used by individuals worldwide for the management of common ailments, even though most are not without risks. Acalypha indica is a popular medicinal plant consumed in some Asian countries. CASE PRESENTATION: This case report presents a 40-year-old previously unevaluated Sri Lankan female and her 8-year-old son who presented with severe glucose-6-phosphate dehydrogenase (G6PD) deficiency related acute intravascular oxidative haemolysis and methaemoglobinaemia precipitated by Acalypha indica consumption, successfully managed with supportive care and blood transfusion.

conclusionsThis case highlights the potential hemolytic and methaemoglobinaemic effects of ingesting oxidant herbal products and the importance of considering such exposures in patients presenting with hemolysis and multiorgan involvement, particularly in communities where herbal product intake is popular. Healthcare providers should be aware of the risks associated with traditional remedies and maintain a high index of suspicion to ensure prompt recognition and appropriate management.

Indexed as

AcalyphaGlucosephosphate Dehydrogenase DeficiencyMethemoglobinemiaPlants, MedicinalAdultChildFemaleHemolysisHumansMaleOxidative StressAcalypha indicaG6PD deficiencyMethaemoglobinaemiaOxidative haemolysis

Identifiers

PMID38500232
PMCPMC10949590
OpenAlexW4394740630

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.