Evidence map›Paper›PMID 38499858›Full record

ArticleScientific reports2024

The impact of brominated flame retardants (BFRs) on pulmonary function in US adults: a cross-sectional study based on NHANES (2007-2012).

Haiyan Mao, Tong Lin, Shanshan Huang, Zhenye Xie, Shaofeng Jin, Xingkai Shen, Yuhong Jin, Yi Ding

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Haiyan MaoDepartment of Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, 315100, China.
Tong LinDepartment of Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, 315100, China.
Shanshan HuangDepartment of Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, 315100, China.
Zhenye XieDepartment of Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, 315100, China.
Shaofeng JinDepartment of Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, 315100, China.
Xingkai ShenDepartment of Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, 315100, China.
Yuhong JinDepartment of Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, 315100, China. jinyuhong2023@163.com.
Yi DingDepartment of Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, 315100, China. dingdingnb@163.com.

Funding

The present work was supported by Medical and Health Science and Technology Project of Zhejiang Province 2023KY244
6 · The paper itself

Abstract

Brominated flame retardants (BFRs) are a group of chemicals widely used in various applications to prevent or slow down the spread of fire. However, they have adverse effects on human health. There is a relative scarcity of population-based studies regarding BFRs, particularly their impact on the respiratory system. This study aimed to investigate the influence of BFRs on pulmonary function using data from the National Health and Nutrition Examination Survey. The study found that elevated serum concentrations of certain BFRs were associated with pulmonary ventilatory dysfunction. Adjusted analyses revealed positive correlations between PBDE47, PBDE183, and PBDE209 concentrations and ventilatory dysfunction. The analysis of mixed BFRs showed a positive relationship with pulmonary ventilation dysfunction, with PBDE47 making the most significant contribution. Our study demonstrates that both individual and combined BFRs exposure can lead to impaired pulmonary ventilation function. These findings provide evidence of the adverse effects of BFRs on lung function, emphasizing the importance of further investigating the potential health consequences of these compounds. Further large-scale longitudinal studies are needed to investigate this relationship in the future.

Indexed as

Drug-Related Side Effects and Adverse ReactionsFlame RetardantsHydrocarbons, BrominatedAdultCross-Sectional StudiesHalogenated Diphenyl EthersHumansLungNutrition SurveysFlame RetardantsHalogenated Diphenyl EthersHydrocarbons, BrominatedBrominated flame retardantsCross-sectional studyPulmonary functionVentilatory dysfunction

Identifiers

PMID38499858
PMCPMC10948772

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.