Evidence map›Paper›PMID 38499733›Full record

ArticleDigestive diseases and sciences2024

Added Value of

Lukas Michaja Balsiger, Els Houben, Tim Vanuytsel, Marc van Ranst, Jan Tack, Kristin Verbeke

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Digestive diseases and sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lukas Michaja BalsigerTranslational Research Center for Gastrointestinal Disorders, KU Leuven, Herestraat 49, 3000, Leuven, Belgium. lukasmichaja.balsiger@kuleuven.be.ORCID http://orcid.org/0000-0001-7399-8500
Els HoubenTranslational Research Center for Gastrointestinal Disorders, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Tim VanuytselTranslational Research Center for Gastrointestinal Disorders, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Marc van RanstDepartment of Laboratory Medicine Cosis, University Hospitals Leuven, Leuven, Belgium.
Jan TackTranslational Research Center for Gastrointestinal Disorders, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Kristin VerbekeTranslational Research Center for Gastrointestinal Disorders, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
KU Leuven · BERega Institute for Medical Research · BE

Funding

FWO Vlaandern Senior clinical research mandateOnderzoeksraad, KU Leuven MethusalemSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung P500PM_206612Swiss National Science Foundation 206612
6 · The paper itself

Abstract

introductionDiagnosing lactose malabsorption is usually based on hydrogen excretion in breath after a lactose challenge. However, a proportion of subjects with lactose malabsorption will not present a rise in hydrogen. Measuring excretion of methane or stable isotope labeled

objectiveThe aim of the study was to assess the performance of measuring methane and

methodsIndividuals referred for lactose breath testing and healthy controls were included. Participants received

results151 subjects participated in the study, 50 of which presented a lactase non-persistent genotype. Of these, 72% were correctly diagnosed through hydrogen excretion of ≥ 20 ppm above baseline. In subjects with normal hydrogen excretion, cumulative

conclusionsIn individuals with genetically demonstrated lactase non-persistence and negative hydrogen breath test, the use of

Indexed as

Breath TestsCarbon IsotopesHydrogenLactaseLactose IntoleranceMethaneAdultCarbon DioxideCase-Control StudiesFemaleGenotypeHumansLactoseMaleMiddle AgedProof of Concept StudyCarbon DioxideCarbon IsotopesHydrogenLactaseLactoseMethaneBreath testsHydrogenLactaseLactose intolerance

Identifiers

PMID38499733
PMCPMC7616739
OpenAlexW4392906196

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.