ArticleNPJ Parkinson's disease2024
Turning alterations detected by mobile health technology in idiopathic REM sleep behavior disorder.
Article in NPJ Parkinson's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Motor features that distinguish isolated REM sleep behavior disorder patients from healthy controls: A systematic review.Journal of Parkinson's disease · 2025Pooled it
- Spatio-temporal gait signatures across prodromal and early Parkinson's disease in two independent cohorts.Scientific reports · 2026Article
- Wearable Inertial Sensor Analysis of Turning Performance Reveals Motor Reserve Effects in Drug-Naïve Parkinson's Disease.Sensors (Basel, Switzerland) · 2026Article
- Association of wearable sensor-based gait analysis with phenoconversion trajectories in idiopathic REM sleep behavior disorder.NPJ Parkinson's disease · 2026Article
- Turning Slowly Predicts Future Diagnosis of Parkinson's Disease: A Decade-Long Longitudinal Analysis.Annals of neurology · 2026Article
- Isolated REM Sleep Behaviour Disorder-Is Screening Possible?Journal of sleep research · 2025Review
- Extensive digital health technology assessment detects subtle motor impairment in mild and asymptomatic Pompe disease.Scientific reports · 2025Article
- Association Between Turn Impairments and Cognitive Function in Parkinson Disease.Aging medicine (Milton (N.S.W)) · 2025Article
- Identifying Subtle Motor Deficits Before Parkinson's Disease is Diagnosed: What to Look for?Journal of Parkinson's disease · 2024Review
- Too little or too much nocturnal movements in Parkinson's disease: A practical guide to managing the unseen.Clinical parkinsonism & related disorders · 2024Article
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 2 countries.
Funding
Abstract
Idiopathic REM sleep Behavior Disorder (iRBD) is a condition at high risk of developing Parkinson's disease (PD) and other alpha-synucleinopathies. The aim of the study was to evaluate subtle turning alterations by using Mobile health technology in iRBD individuals without subthreshold parkinsonism. A total of 148 participants (23 persons with polysomnography-confirmed iRBD without subthreshold parkinsonism, 60 drug-naïve PD patients, and 65 age-matched controls were included in this prospective cross-sectional study. All underwent a multidimensional assessment including cognitive and non-motor symptoms assessment. Then a Timed-Up-and-Go test (TUG) at normal and fast speed was performed using mobile health technology on the lower back (Rehagait®, Hasomed, Germany). Duration, mean, and peak angular velocities of the turns were compared using a multivariate model correcting for age and sex. Compared to controls, PD patients showed longer turn durations and lower mean and peak angular velocities of the turns in both TUGs (all p ≤ 0.001). iRBD participants also showed a longer turn duration and lower mean (p = 0.006) and peak angular velocities (p < 0.001) compared to controls, but only in the TUG at normal speed. Mobile health technology assessment identified subtle alterations of turning in subjects with iRBD in usual, but not fast speed. Longitudinal studies are warranted to evaluate the value of objective turning parameters in defining the risk of conversion to PD in iRBD and in tracking motor progression in prodromal PD.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.