Evidence map›Paper›PMID 38499518›Full record

ArticleNature communications2024

Population-wide cerebellar growth models of children and adolescents.

Carolin Gaiser, Rick van der Vliet, Augustijn A A de Boer, Opher Donchin, Pierre Berthet, Gabriel A Devenyi, M Mallar Chakravarty, Jörn Diedrichsen, Andre F Marquand, Maarten A Frens and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
32.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Carolin GaiserDepartment of Neuroscience, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands.ORCID 0000-0003-3658-1946
Rick van der VlietDepartment of Neuroscience, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands.
Augustijn A A de BoerDonders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen, Nijmegen, The Netherlands.
Opher DonchinDepartment of Biomedical Engineering, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
Pierre BerthetDepartment of Psychology, University of Oslo, Oslo, Norway.
Gabriel A DevenyiCerebral Imaging Centre, Douglas Research Centre, McGill University, Montreal, Canada.ORCID 0000-0002-7766-1187
M Mallar ChakravartyCerebral Imaging Centre, Douglas Research Centre, McGill University, Montreal, Canada.
Jörn DiedrichsenWestern Institute of Neuroscience, Western University, London, Ontario, Canada.ORCID 0000-0003-0264-8532
Andre F MarquandDonders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen, Nijmegen, The Netherlands.ORCID 0000-0001-5903-203X
Maarten A FrensDepartment of Neuroscience, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands. m.frens@erasmusmc.nl.ORCID 0000-0002-0752-2034
Ryan L MuetzelDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC - Sophia Children's Hospital, University Medical Centre Rotterdam, Rotterdam, The Netherlands.ORCID 0000-0003-3215-1287
Erasmus MC · NLMcGill University · CARadboud University Nijmegen · NLBen-Gurion University of the Negev · ILOslo University Hospital · NOWestern University · CA

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek (Netherlands Organisation for Scientific Research) 2021.042Wellcome TrustWellcome Trust 215698/Z/19/ZWellcome Trust (Wellcome) BRAINCHART 215698/Z/19/Z
6 · The paper itself

Abstract

In the past, the cerebellum has been best known for its crucial role in motor function. However, increasingly more findings highlight the importance of cerebellar contributions in cognitive functions and neurodevelopment. Using a total of 7240 neuroimaging scans from 4862 individuals, we describe and provide detailed, openly available models of cerebellar development in childhood and adolescence (age range: 6-17 years), an important time period for brain development and onset of neuropsychiatric disorders. Next to a traditionally used anatomical parcellation of the cerebellum, we generated growth models based on a recently proposed functional parcellation. In both, we find an anterior-posterior growth gradient mirroring the age-related improvements of underlying behavior and function, which is analogous to cerebral maturation patterns and offers evidence for directly related cerebello-cortical developmental trajectories. Finally, we illustrate how the current approach can be used to detect cerebellar abnormalities in clinical samples.

Indexed as

CerebellumCognitionAdolescentChildHumansMagnetic Resonance ImagingNeuroimaging

Identifiers

PMID38499518
PMCPMC10948906
OpenAlexW4392897364

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.