Evidence map›Paper›PMID 38499328›Full record

ArticleLife science alliance2024

A genetic screen to uncover mechanisms underlying lipid transfer protein function at membrane contact sites.

Shirish Mishra, Vaishnavi Manohar, Shabnam Chandel, Tejaswini Manoj, Subhodeep Bhattacharya, Nidhi Hegde, Vaisaly R Nath, Harini Krishnan, Corinne Wendling, Thomas Di Mattia and 4 more

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Editorial on Special Collection inContact (Thousand Oaks (Ventura County, Calif.))
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Shirish MishraNational Centre for Biological Sciences-TIFR, GKVK Campus, Bangalore, India.ORCID 0000-0001-7915-8297
Vaishnavi ManoharNational Centre for Biological Sciences-TIFR, GKVK Campus, Bangalore, India.
Shabnam ChandelNational Centre for Biological Sciences-TIFR, GKVK Campus, Bangalore, India.
Tejaswini ManojNational Centre for Biological Sciences-TIFR, GKVK Campus, Bangalore, India.ORCID 0009-0009-2528-8702
Subhodeep BhattacharyaNational Centre for Biological Sciences-TIFR, GKVK Campus, Bangalore, India.ORCID 0009-0009-0334-9068
Nidhi HegdeNational Centre for Biological Sciences-TIFR, GKVK Campus, Bangalore, India.
Vaisaly R NathNational Centre for Biological Sciences-TIFR, GKVK Campus, Bangalore, India.ORCID 0000-0002-0245-1855
Harini KrishnanNational Centre for Biological Sciences-TIFR, GKVK Campus, Bangalore, India.
Corinne WendlingUniversité de Strasbourg, CNRS, Inserm, IGBMC UMR 7104- UMR-S 1258, Illkirch, France.ORCID 0000-0001-7171-3890
Thomas Di MattiaUniversité de Strasbourg, CNRS, Inserm, IGBMC UMR 7104- UMR-S 1258, Illkirch, France.
Arthur MartinetUniversité de Strasbourg, CNRS, Inserm, IGBMC UMR 7104- UMR-S 1258, Illkirch, France.ORCID 0000-0002-9286-306X
Prasanth ChimataNational Centre for Biological Sciences-TIFR, GKVK Campus, Bangalore, India.
Fabien AlpyUniversité de Strasbourg, CNRS, Inserm, IGBMC UMR 7104- UMR-S 1258, Illkirch, France.ORCID 0000-0002-0526-0720
Padinjat RaghuNational Centre for Biological Sciences-TIFR, GKVK Campus, Bangalore, India praghu@ncbs.res.in.ORCID 0000-0003-3578-6413
National Centre for Biological Sciences · INCentre National de la Recherche Scientifique · FR

Funding

DBT-Wellcome Trust India Alliance IA/E/17/1/503653DBT-Wellcome Trust India Alliance IA/S/14/2/501540Wellcome Trust
6 · The paper itself

Abstract

Lipid transfer proteins mediate the transfer of lipids between organelle membranes, and the loss of function of these proteins has been linked to neurodegeneration. However, the mechanism by which loss of lipid transfer activity leads to neurodegeneration is not understood. In

Indexed as

Carrier ProteinsDrosophila ProteinsRetinal DegenerationAnimalsDrosophilaHumansLipidsPhospholipid Transfer ProteinsCarrier ProteinsDrosophila ProteinsLipidslipid transfer proteinPhospholipid Transfer Proteins

Identifiers

PMID38499328
PMCPMC10948934
OpenAlexW4392913618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.