Evidence map›Paper›PMID 38499080›Full record

SynthesisJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2024

Endovascular outcomes for anterior choroidal artery aneurysms: systematic review and meta-analysis.

Yigit Can Senol, Atakan Orscelik, Basel Musmar, Sherief Ghozy, Gokce Belge Bilgin, Hassan Kobeissi, Madona Pakkam, David F Kallmes, Ramanathan Kadirvel

Open access · greenAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yigit Can SenolDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA. Electronic address: ygtsenol@gmail.com.
Atakan OrscelikDepartment of Neurologic Surgery, Medical University of South Carolina, SC, USA.
Basel MusmarDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Sherief GhozyDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA; Department of Radiology, Mayo Clinic, Rochester, MN, USA.
Gokce Belge BilginDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Hassan KobeissiDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Madona PakkamDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
David F KallmesDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Ramanathan KadirvelDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Arizona · USMayo Clinic · USMedical University of South Carolina · US

Funding

Computational and Biological Approach to Flow DiversionR01NS076491 · NINDS · MAYO CLINIC ROCHESTER · PI Juan R Cebral, DAVID F KALLMES · 2011 to 2026
$7.4M
NINDS NIH HHS R01 NS076491
6 · The paper itself

Abstract

backgroundAnterior choroidal artery (AchoA) aneurysms are relatively rare compared to other types of aneurysms. However, the occurrence of transient or permanent occlusion of the choroidal artery during endovascular or surgical treatment is an uncommon but potentially serious complication. In this study, we aim to investigate the safety and efficacy profile of endovascular treatment (EVT) for AchoA aneurysms.

methodsThe primary outcome of interest was angiographic and clinical outcomes. Secondary outcome variables transient and permanent ischemic complications, symptomatic choroidal artery occlusion and retreatment rates. A random-effects model was used to calculate prevalence rates and their corresponding 95 % confidence intervals (CI), and subgroup analyses were performed to assess the complication rates for Type 1(arterial type, directly arising from ICA) and Type 2(neck type, arising from AchoA branch)) AchoA aneurysms, ruptured vs non-ruptured and for flow diverter (FD) treatment versus coiling.

resultsOur study included 10 studies with 416 patients with 430 AchoA aneurysms. The overall good clinical outcome rate (mRS score 0-2) is 94.5 % with a retreatment rate of 2.0 %. A subgroup analysis showed no statistical difference between coiling(75.3 %) and flow diverter(80.9 %) treatment in terms of complete occlusion(p-value:0.62). Overall permanent complication rate is 1.4 % (p-value:0.54) and transient ischemic complications rate is 4.2 %(p-value:0.61). Symptomatic choroidal artery occlusion rate is 0.8 %(p-value:0.51)Type 2 AchoA aneurysms had a significantly higher complication rate of 9.8 % (p-value<0.05) compared to Type 1 aneurysms. Unruptured aneurysms have significantly better clinical outcomes than ruptured aneurysms(OR: 0.11; [0.02;0.5], p-value:<0.05)

conclusionEndovascular treatment of AchoA aneurysms demonstrated positive clinical results, with low rates of retreatment and complications. Coiling and flow diverters proved similar outcomes in achieving aneurysm occlusion. Ruptured aneurysms have lower good clinical outcomes comparing to unruptured aneurysms. Type 2 AchoA aneurysms had a higher risk of complications compared to Type 1.

Indexed as

Endovascular ProceduresIntracranial AneurysmAdultAgedEmbolization, TherapeuticFemaleHumansMaleMiddle AgedRisk AssessmentRisk FactorsTreatment OutcomeAneurysmAnterior Choroidal arterycoilingEndovascularFlow diverterstent

Identifiers

PMID38499080
PMCPMC11088492
OpenAlexW4393135363

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.