Evidence map›Paper›PMID 38499039›Full record

ArticleNature2024

Structural insights into vesicular monoamine storage and drug interactions.

Jin Ye, Huaping Chen, Kaituo Wang, Yi Wang, Aaron Ammerman, Samjhana Awasthi, Jinbin Xu, Bin Liu, Weikai Li

Open access · greenAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jin YeDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0003-1004-5344
Huaping ChenDepartment of Radiology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0002-9835-5138
Kaituo WangDepartment of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-5922-7109
Yi WangDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, MO, USA.
Aaron AmmermanDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0001-9245-4015
Samjhana AwasthiDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, MO, USA.
Jinbin XuDepartment of Radiology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0002-2120-8287
Bin LiuThe Hormel Institute, University of Minnesota, Austin, MN, USA. liu00794@umn.edu.ORCID 0000-0002-6581-780X
Weikai LiDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, MO, USA. weikai@wustl.edu.ORCID 0000-0002-8711-1904
Washington University in St. Louis · USUniversity of Copenhagen · DKUniversity of Minnesota · US

Funding

STRUCTURAL AND FUNCTIONAL BASIS OF THE VITAMIN K CYCLER01HL121718 · NHLBI · WASHINGTON UNIVERSITY · PI Weikai Li · 2014 to 2026
$5.2M
NEW CHEMICAL PROBES ENABLE MASS SPECTROMETRY-BASED FOOTPRINTING OF HUMAN PROTEIN STRUCTURE IN LIPID MEMBRANES AND CELLSR01GM131008 · NIGMS · WASHINGTON UNIVERSITY · PI MICHAEL L GROSS, Weikai Li · 2019 to 2026
$3.8M
Dissect the mechanisms of selective regional vulnerability in Lewy Body Dementias via comparative snRNA-seq analysisR01NS123571 · NINDS · WASHINGTON UNIVERSITY · PI XU, JINBIN, ZHAO, GUOYAN · 2021 to 2025
$3.6M
Defining the partner interaction network of the tetraspanin CD53 in regulating B cell traffickingR01AI158500 · NIAID · WASHINGTON UNIVERSITY · PI Weikai Li, LAURA G. SCHUETTPELZ · 2022 to 2026
$2.8M
POSTMORTEM VALIDATION OF BIOMARKERS FOR IMAGING PARKINSON DISEASER01NS092865 · NINDS · WASHINGTON UNIVERSITY · PI XU, JINBIN · 2016 to 2020
$1.7M
NHLBI NIH HHS R01 HL121718NIAID NIH HHS R01 AI158500NIGMS NIH HHS R01 GM131008NINDS NIH HHS R01 NS092865NINDS NIH HHS R01 NS123571
6 · The paper itself

Abstract

Biogenic monoamines-vital transmitters orchestrating neurological, endocrinal and immunological functions

Indexed as

Biogenic MonoaminesDrug InteractionsVesicular Monoamine Transport Proteins1-Methyl-4-phenylpyridiniumAmphetamineBinding SitesCryoelectron MicroscopyDopamineHumansModels, MolecularNitro CompoundsNorepinephrineProtein BindingProtonsPyrimidinesReserpine1-Methyl-4-phenylpyridinium6-(2,4-dinitrophenylthio)-4-(3-nitrophenyl)-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazolo(3,4-d)pyrimidineAmphetamineBiogenic MonoaminesDopamineNitro CompoundsNorepinephrineProtonsPyrimidinesReserpineSerotoninSLC18A1 protein, humanVesicular Monoamine Transport Proteins

Identifiers

PMID38499039
PMCPMC11070986
OpenAlexW4392906584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.