Evidence map›Paper›PMID 38498205›Full record

ArticleOrthopadie (Heidelberg, Germany)2024

Peracetic acid sterilized tendon and ligament allografts for knee reconstruction : For anterior cruciate ligament (ACL), posterior cruciate ligament (PCL) and complex knee surgery.

Philipp Ahrens, Gudrun H Borchert, Christin Freutel, Norus Ahmed, Jan C Brune

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Orthopadie (Heidelberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Philipp AhrensOrthoplus Munich, Alte Börse, Lehnbachplatz 2a, 80333, Munich, Germany. p.ahrens@orthoplus-muc.de.
Gudrun H BorchertDr. Borchert Medical Information Management, Egelsbacher Str. 39e, 63225, Langen, Germany.
Christin FreutelR&D, German Institute for Cell and Tissue Replacement (DIZG, gGmbH), Haus 42, Köpenicker Str. 325, 12555, Berlin, Germany.
Norus AhmedR&D, German Institute for Cell and Tissue Replacement (DIZG, gGmbH), Haus 42, Köpenicker Str. 325, 12555, Berlin, Germany.
Jan C BruneR&D, German Institute for Cell and Tissue Replacement (DIZG, gGmbH), Haus 42, Köpenicker Str. 325, 12555, Berlin, Germany.
German Institute for Cell and Tissue Replacement · DEFive Continents Museum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of allografts and autografts has been met with mixed views on whether allografts are a suitable alternative to autografts. QUESTION: We aimed to investigate if chemically sterilized allografts show similar rerupture rates to those reported in the literature for allografts and autografts in anterior (ACL) and posterior cruciate ligaments (PCL) and complex knee surgery. MATERIALS AND

methodsRetrospective data on knee reconstructions performed between 2011 and 2015 with tendon/ligamnet allografts sterilized with peracetic acid were collected in the form of a questionnaire. The inclusion criteria of 2 years for each patient were met by 38 patients, representing 22 ACL reconstructions, 5 PCL reconstructions, 3 OTHER surgeries, including the Larson technique and medial patellofemoral ligament (MPFL) reconstruction and 8 COMPLEX surgeries. The main endpoints were rerupture and complication rate. Secondary endpoints included stability of the knee (Lachman test, Pivot shift test) and the range of motion.

resultsThe rerupture rate was 7.9% (3 grafts). Reruptures only occurred in the ACL group. No reruptures were observed in the PCL, OTHER and COMPLEX surgery groups. Stability improved significantly after surgery and the range of motion returned to values similar to that of healthy knees.

conclusionsTendon allografts sterilized with peracetic acid show promising low rerupture rates and good clinical scores and the results are comparable to the literature on autografts and other allografts.

Indexed as

AllograftsPeracetic AcidSterilizationTendonsAdultAnterior Cruciate Ligament ReconstructionFemaleHumansMaleMiddle AgedPosterior Cruciate LigamentPosterior Cruciate Ligament ReconstructionRetrospective StudiesTransplantation, HomologousPeracetic AcidACL and PCL reconstructionAllograftLarson, MPFLPeracetic-acidTendon

Identifiers

PMID38498205
PMCPMC11052767
OpenAlexW4392918500

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.