Evidence map›Paper›PMID 38498203›Full record

ArticlePediatric surgery international2024

Pulmonary vasculature development in congenital diaphragmatic hernia: a novel automated quantitative imaging analysis.

Emrah Aydın, Furkan Durmuş, Nilhan Torlak, Marc Oria, Nilgün Güler Bayazıt, Esin Öztürk Işık, Birol Aslanyürek, Jose L Peiro

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Article in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Emrah AydınDivision of Pediatric General and Thoracic Surgery, The Center for Fetal and Placental Research, Cincinnati Fetal Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA. dremrahaydin@yahoo.com.
Furkan DurmuşInstitute of Biomedical Engineering, Boğaziçi University, Istanbul, Turkey.
Nilhan TorlakDivision of Pediatric General and Thoracic Surgery, The Center for Fetal and Placental Research, Cincinnati Fetal Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.
Marc OriaDivision of Pediatric General and Thoracic Surgery, The Center for Fetal and Placental Research, Cincinnati Fetal Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.
Nilgün Güler BayazıtDepartment A: Mathematical Engineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul, Turkey.
Esin Öztürk IşıkInstitute of Biomedical Engineering, Boğaziçi University, Istanbul, Turkey.
Birol AslanyürekDepartment A: Mathematical Engineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul, Turkey.
Jose L PeiroDivision of Pediatric General and Thoracic Surgery, The Center for Fetal and Placental Research, Cincinnati Fetal Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.
Cincinnati Children's Hospital Medical Center · USBoğaziçi University · TRYıldız Technical University · TRUniversity of Cincinnati Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeImpaired fetal lung vasculature determines the degree of pulmonary hypertension in the congenital diaphragmatic hernia (CDH). This study aims to demonstrate the morphometric measurements that differ in pulmonary vessels of fetuses with CDH.

methodsNitrofen-induced CDH Sprague-Dawley rat fetuses were scanned with microcomputed tomography. The analysis of the pulmonary vascular tree was performed with artificial intelligence.

resultsThe number of segments in CDH was significantly lower than that in the control group on the left (U = 2.5, p = 0.004) and right (U = 0, p = 0.001) sides for order 1(O1), whereas there was a significant difference only on the right side for O2 and O3. The pooled element numbers in the control group obeyed Horton's law (R

conclusionAccording to these findings, CDH not only reduced the amount of small order elements, but also destroyed the fractal structure of the pulmonary arterial trees.

Indexed as

Hernias, Diaphragmatic, CongenitalAnimalsArtificial IntelligenceDisease Models, AnimalLungPhenyl EthersRatsRats, Sprague-DawleyX-Ray MicrotomographyPhenyl EthersFetal pulmonary circulationLung developmentLung vasculatureMicrocomputed tomographyVessel morphology

Identifiers

PMID38498203
OpenAlexW4392919678

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.