Evidence map›Paper›PMID 38498182›Full record

ArticleCalcified tissue international2024

Fracture Risk and Health Profiles Differ According to Relationship Status: Findings from the Hertfordshire Cohort Study.

Leo D Westbury, Camille Pearse, Gregorio Bevilacqua, Nicholas R Fuggle, Kate A Ward, Cyrus Cooper, Elaine M Dennison

Abstract read
In one paragraph

Article in Calcified tissue international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leo D WestburyMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.ORCID 0009-0008-5853-8096
Camille PearseMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Gregorio BevilacquaMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Nicholas R FuggleMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Kate A WardMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Cyrus CooperMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Elaine M DennisonMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK. emd@mrc.soton.ac.uk.

Funding

Medical Research Council MC_PC_21001Medical Research Council MC_PC_21003Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/2Medical Research Council MRC_MC_UP_A620_1014
6 · The paper itself

Abstract

Registry studies have suggested associations between relationship status and fracture risk. We considered associations between relationship status and incident fracture in the Hertfordshire Cohort Study, comprising community-dwelling older adults, and explored associations between socioeconomic and lifestyle factors with relationship status. 2997 participants completed a baseline questionnaire (1998-2004) and clinic visit. Participants were followed up until December 2018 using Hospital Episode Statistics, which report clinical outcomes using codes from the 10th revision of the International Classification of Diseases (ICD-10); these codes were used to ascertain incident fractures. Relationship status (not currently married/cohabiting vs currently married/cohabiting) at baseline was examined in relation to incident fracture using Cox regression. Associations between baseline characteristics and relationship status were examined using logistic regression. Mean baseline age was 66.2 years. 80% were married/cohabiting at baseline; 15% had an incident fracture (mean (SD) follow-up duration: 14.4 (4.5) years). The following were related to greater likelihood of not being married/cohabiting: older age (women only); higher BMI (women only); current smoking; high alcohol consumption (men only); poorer diet quality (men only); lower physical activity; leaving school before age 15 (women only); and not owning one's home. Those not married/cohabiting had greater risk of incident fracture compared to those who were (age-adjusted hazard ratios (95% CI) 1.58 (1.06, 2.38) among men, 1.35 (1.06, 1.72) among women); associations were attenuated after accounting for the above factors associated with relationship status in the corresponding sex. This suggests that differences in health profiles and lifestyle according to relationship status may explain the association between relationship status and fracture risk.

Indexed as

Fractures, BoneAgedAged, 80 and overCohort StudiesFemaleHumansIncidenceLife StyleMaleMiddle AgedRisk FactorsEpidemiologyFractureLifestyleOsteoporosisRelationship statusSocioeconomic

Identifiers

PMID38498182
PMCPMC11060979

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.