Evidence map›Paper›PMID 38497810›Full record

ArticleTraffic injury prevention2024

Effects of kratom on driving: Results from a cross-sectional survey, ecological momentary assessment, and pilot simulated driving Study.

C Austin Zamarripa, Tory R Spindle, Leigh V Panlilio, Justin C Strickland, Jeffrey D Feldman, Matthew D Novak, David H Epstein, Kelly E Dunn, Christopher R McCurdy, Abhisheak Sharma and 5 more

Abstract read
In one paragraph

Article in Traffic injury prevention, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

C Austin ZamarripaDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Tory R SpindleDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Leigh V PanlilioReal-World, Assessment, Prediction, Treatment Unit, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland, USA.
Justin C StricklandDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jeffrey D FeldmanReal-World, Assessment, Prediction, Treatment Unit, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland, USA.
Matthew D NovakDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
David H EpsteinReal-World, Assessment, Prediction, Treatment Unit, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland, USA.
Kelly E DunnDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Christopher R McCurdyDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Abhisheak SharmaDepartment of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Michelle A KuntzDepartment of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Sushobhan MukhopadhyayDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Kanumuri Siva Rama RajuDepartment of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Jeffrey M RogersSan Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California, USA.
Kirsten E SmithDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Funding

Real-Time Assessment of Drug Use, Along with Mental States and EnvironmentsZIADA000499 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI EPSTEIN, DAVID · 2009 to 2025
$19.9M
Training in Research on Addictions in Interdisciplinary NeuroAIDS (TRAIN)T32DA031098 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello, DAVID J MOORE · 2011 to 2026
$4.6M
NIDA NIH HHS K99 DA055571NIDA NIH HHS T32 DA031098
6 · The paper itself

Abstract

objectivesDespite widespread kratom use, there is a lack of knowledge regarding its effects on driving. We evaluated the self-reported driving behaviors of kratom consumers and assessed their simulated-driving performance after self-administering kratom products.

methodsWe present results from: 1) a remote, national study of US adults who regularly use kratom, and 2) an in-person substudy from which we re-recruited participants. In the national study (

resultsOver 90% of participants surveyed self-reported driving under the influence of kratom. Most reported low rates of risky driving behavior and expressed high confidence in their driving ability after taking kratom. This was consistent with EMA findings: participants reported feeling confident in their driving ability and perceived little impairment within 15-180 min after using kratom. In the in-person substudy, there were no significant changes in simulated driving performance after taking kratom.

conclusionsUsing kratom before driving appears routine, however, self-reported and simulated driving findings suggest kratom effects at self-selected doses among regular kratom consumers do not produce significant changes in subjective and objective measures of driving impairment. Research is needed to objectively characterize kratom's impact on driving in regular and infrequent consumers.

Indexed as

MitragynaAccidents, TrafficAdultCross-Sectional StudiesEcological Momentary AssessmentHumansSelf Reportcross-sectional surveydriving simulatorecological momentary assessmentKratom

Identifiers

PMID38497810
PMCPMC11149710

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.