Evidence map›Paper›PMID 38497708›Full record

ArticleJournal of proteome research2024

Single Cell Analysis of Proteoforms.

Pei Su, Michael A R Hollas, Fatma Ayaloglu Butun, Vijaya Lakshmi Kanchustambham, Stanislav Rubakhin, Namrata Ramani, Joseph B Greer, Bryan P Early, Ryan T Fellers, Michael A Caldwell and 3 more

Abstract read
In one paragraph

Article in Journal of proteome research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Subcellular localization as a driver of protein function.Nature reviews. Molecular cell biology · 2026
    Review
  2. Article
  3. Probing Proteoform Heterogeneity From Single Human Oocytes.Molecular & cellular proteomics : MCP · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Plasma-Derived Extracellular Vesicle Proteomics.Journal of proteome research · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Top-down proteomics.Nature reviews. Methods primers · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Pei SuDepartments of Molecular Biosciences, Chemistry, Chemical and Biological Engineering, and Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0001-6148-0181
Michael A R HollasDepartments of Molecular Biosciences, Chemistry, Chemical and Biological Engineering, and Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-0797-3134
Fatma Ayaloglu ButunProteomics Center of Excellence, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois 60208, United States.
Vijaya Lakshmi KanchustambhamProteomics Center of Excellence, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-2927-1045
Stanislav RubakhinBeckman Institute and Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0003-0437-1493
Namrata RamaniDepartment of Materials Science and Engineering, Northwestern University, Evanston, Illinois 60208, United States.
Joseph B GreerDepartments of Molecular Biosciences, Chemistry, Chemical and Biological Engineering, and Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, United States.
Bryan P EarlyDepartments of Molecular Biosciences, Chemistry, Chemical and Biological Engineering, and Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, United States.
Ryan T FellersDepartments of Molecular Biosciences, Chemistry, Chemical and Biological Engineering, and Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, United States.
Michael A CaldwellProteomics Center of Excellence, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-8636-0706
Jonathan V SweedlerBeckman Institute and Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0003-3107-9922
Jared O KafaderDepartments of Molecular Biosciences, Chemistry, Chemical and Biological Engineering, and Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-5359-264X
Neil L KelleherDepartments of Molecular Biosciences, Chemistry, Chemical and Biological Engineering, and Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-8815-3372

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Devalingam Mahalingam · 1993 to 2026
$153.9M
The UIUC Neuroproteomics Center on Cell-Cell SignalingP30DA018310 · NIDA · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI Jonathan V. Sweedler · 2004 to 2026
$24.9M
TR&D 7: Cell Specific ProteomicsP41GM108569 · NIGMS · NORTHWESTERN UNIVERSITY · PI KELLEHER, NEIL L · 2015 to 2024
$13.6M
Renewable and Specific Affinity Reagents for Mapping Proteoforms in Human TissuesUH3CA246635 · NCI · NORTHWESTERN UNIVERSITY · PI KELLEHER, NEIL L · 2019 to 2021
$1.4M
Single Cell Proteoform Profiling using Top-Down Mass SpectrometryK99AI183290 · NIAID · NORTHWESTERN UNIVERSITY · PI SU, PEI · 2024 to 2025
$249k
NCI NIH HHS P30 CA060553NCI NIH HHS UH3 CA246635NIAID NIH HHS K99 AI183290NIDA NIH HHS P30 DA018310NIGMS NIH HHS P41 GM108569
6 · The paper itself

Abstract

We introduce single cell Proteoform imaging Mass Spectrometry (

Indexed as

Mass SpectrometryProteomicsSingle-Cell AnalysisHumansProteomeProteomeindividual ion mass spectrometrymass spectrometrynano-DESIproteoform assignment scoresingle celltop-down proteomics

Identifiers

PMID38497708
PMCPMC11406863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.