Evidence map›Paper›PMID 38497588›Full record

ArticleNano letters2024

Multicolor Long-Term Single-Particle Tracking Using 10 nm Upconverting Nanoparticles.

João F Shida, Kaibo Ma, Harrison W Toll, Omar Salinas, Xiaojie Ma, Chunte Sam Peng

Abstract read
In one paragraph

Article in Nano letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Sensing with (One or Many) Upconverting Nanoparticles.Accounts of chemical research · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Enhanced Single-Particle Upconversion Imaging via Energy Migration Boosting.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Review
  10. Visualising sub-second dynamics of nanoparticle extravasationbioRxiv : the preprint server for biology · 2025
    Article
  11. Sub-10 nm YbRSC advances · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

João F ShidaDepartment of Chemistry, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts 02139, United States.ORCID 0000-0002-7333-3274
Kaibo MaDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States.ORCID 0009-0004-1415-0023
Harrison W TollDepartment of Chemistry, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts 02139, United States.ORCID 0000-0002-3653-2426
Omar SalinasDepartment of Chemistry, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts 02139, United States.ORCID 0009-0004-5678-6177
Xiaojie MaBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, United States.ORCID 0000-0001-6565-0627
Chunte Sam PengDepartment of Chemistry, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts 02139, United States.ORCID 0000-0001-8885-2619

Funding

Ultralong-term single-molecule imaging of amyloid precursor protein (APP) processing in Alzheimer's diseaseR00AG065516 · NIA · BROAD INSTITUTE, INC. · PI PENG, CHUNTE · 2023 to 2025
$722k
Ultralong-term single-molecule imaging of amyloid precursor protein (APP) processing in Alzheimer's diseaseK99AG065516 · NIA · STANFORD UNIVERSITY · PI PENG, CHUNTE · 2020 to 2021
$233k
NIA NIH HHS K99 AG065516NIA NIH HHS R00 AG065516
6 · The paper itself

Abstract

Single-particle tracking (SPT) is a powerful technique to unveil molecular behaviors crucial to the understanding of many biological processes, but it is limited by factors such as probe photostability and spectral orthogonality. To overcome these limitations, we develop upconverting nanoparticles (UCNPs), which are photostable over several hours at the single-particle level, enabling long-term multicolor SPT. We investigate the brightness of core-shell UCNPs as a function of inert shell thickness to minimize particle size while maintaining sufficient signal for SPT. We explore different rare-earth dopants to optimize for the brightest probes and find that UCNPs doped with 2% Tm

Indexed as

MicroscopyMulticolor imagingSingle-particle trackingUCNPUpconversion

Identifiers

PMID38497588
PMCPMC11555556

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.