Evidence map›Paper›PMID 38497441›Full record

ArticleJournal of the American Heart Association2024

Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence.

Eero A Haapala, Marja H Leppänen, Earric Lee, Kai Savonen, Jari A Laukkanen, Mika Kähönen, Soren Brage, Timo A Lakka

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Development of the Cardiovascular System During Adolescence.Advances in experimental medicine and biology · 2026
    Review
  4. Cardiopulmonary Benefits of Exercise in Adolescents.Advances in experimental medicine and biology · 2026
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Eero A HaapalaFaculty of Sport and Health Sciences University of Jyväskylä Jyväskylä Finland.ORCID 0000-0001-5096-851X
Marja H LeppänenInstitute of Biomedicine, School of Medicine University of Eastern Finland Kuopio Finland.ORCID 0000-0001-6933-8809
Earric LeeFaculty of Sport and Health Sciences University of Jyväskylä Jyväskylä Finland.ORCID 0000-0003-3490-4262
Kai SavonenFoundation for Research in Health Exercise and Nutrition Kuopio Research Institute of Exercise Medicine Kuopio Finland.ORCID 0000-0002-6871-8153
Jari A LaukkanenInstitute of Public Health and Clinical Nutrition University of Eastern Finland Kuopio Finland.ORCID 0000-0002-3738-1586
Mika KähönenDepartment of Clinical Physiology, Tampere University Hospital and Faculty of Medicine and Health Technology Tampere University Tampere Finland.ORCID 0000-0002-4510-7341
Soren BrageMRC Epidemiology Unit University of Cambridge School of Clinical Medicine Cambridge United Kingdom.ORCID 0000-0002-1265-7355
Timo A LakkaInstitute of Biomedicine, School of Medicine University of Eastern Finland Kuopio Finland.ORCID 0000-0002-9199-2871
University of Eastern Finland · FITampere University Hospital · FIUniversity of Cambridge · GBUniversity of Helsinki · FIUniversity of Jyväskylä · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreased physical activity (PA) may mitigate the negative cardiovascular health effects of sedentary behavior in adolescents. However, the relationship of PA and sedentary time from childhood with cardiac function in adolescence remains underexplored. Therefore, we investigated the associations of cumulative sedentary time and PA from childhood to adolescence with cardiac function in adolescence. METHODS AND

resultsParticipants were 153 adolescents (69 girls) who were aged 6 to 8 years at baseline, 8 to 10 years at 2-year follow-up, and 15 to 17 years at 8-year follow-up. Cumulative sedentary time and PA exposure between baseline and 2-year follow-up and between baseline and 8-year follow-up were measured using a combined accelerometer and heart rate monitor. Cardiac function was assessed using impedance cardiography at 8-year follow-up. The data were analyzed using linear regression analyses adjusted for age and sex. Cumulative moderate to vigorous PA (standardized regression coefficient [β]=-0.323 [95% CI, -0.527 to -0.119]) and vigorous PA (β=-0.295 [95% CI, -0.508 to -0.083]) from baseline to 8-year follow-up were inversely associated with cardiac work at 8-year follow-up. Conversely, cumulative sedentary time had a positive association (β=0.245 [95% CI, 0.092-0.398]). Cumulative vigorous PA from baseline to 8-year follow-up was inversely associated with cardiac work index at 8-year follow-up (β=-0.218 [95% CI, -0.436 to 0.000]).

conclusionsHigher levels of sedentary time and lower levels of PA during childhood were associated with higher cardiac work in adolescence, highlighting the importance of increasing PA and reducing sedentary time from childhood.

Indexed as

ExerciseSedentary BehaviorAdolescentCardiovascular Physiological PhenomenaData CollectionFemaleHumansexerciseheart functionpediatricssedentary behavior

Identifiers

PMID38497441
PMCPMC11010014
OpenAlexW4392897291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.