Evidence map›Paper›PMID 38497333›Full record

ArticleGeriatrics & gerontology international2024

Association of pneumonia admission with polypharmacy and drug use in community-dwelling older people.

Hironobu Hamaya, Taro Kojima, Yukari Hattori, Masahiro Akishita

Open access · hybridAbstract read
In one paragraph

Article in Geriatrics & gerontology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hironobu HamayaDepartment of Geriatrics, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan.
Taro KojimaDepartment of Geriatric Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0003-3857-5267
Yukari HattoriDepartment of Geriatric Medicine, The University of Tokyo, Tokyo, Japan.
Masahiro AkishitaDepartment of Geriatric Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0001-5498-7224
The University of Tokyo · JPTokyo Metropolitan Geriatric Hospital · JP

Funding

Japan Agency for Medical Research and Development 20ek0210107h003Ministry of Health, Labour and Welfare H30-Ninchisho-Ippan-001
6 · The paper itself

Abstract

aimThe purpose of the present study was to clarify the association of pneumonia admission with polypharmacy and specific drug use in community-dwelling older people.

methodsUsing health insurance and long-term care insurance data from Kure city in Japan, we retrospectively collected data for older community-dwelling people (aged ≥65 years) from April 2017 to March 2019. The outcome was pneumonia admission. We carried out multivariate logistic regression analysis to identify the association of pneumonia admission with polypharmacy (≥5 drugs), the use of psychotropic drugs or anticholinergics with adjustment for patient backgrounds, such as comorbidity, and the daily life independence level for the older people with disability.

resultsOf 59 040 older people, 4017 (6.8%) participants were admitted for pneumonia in 2 years. The ratio of polypharmacy, and the use of psychotropic drugs and anticholinergics in the admission group were significantly higher than the non-admission group. Multivariate logistic regression analysis showed that polypharmacy (odds ratio 1.29, 95% confidence interval 1.18-1.41), and the use of conventional antipsychotic drugs (odds ratio 1.39, 95% confidence interval 1.02-1.90), atypical antipsychotic drugs (odds ratio 1.67, 95% confidence interval 1.37-2.05) and anticholinergics (odds ratio 1.22, 95% confidence interval 1.13-1.33) were significantly associated with pneumonia admission.

conclusionThe present results suggest that polypharmacy, and the use of psychotropic drugs and anticholinergics are risk factors for pneumonia admission. Geriatr Gerontol Int 2024; 24: 404-409.

Indexed as

Antipsychotic AgentsIndependent LivingAgedCholinergic AntagonistsHumansPolypharmacyPsychotropic DrugsRetrospective StudiesAntipsychotic AgentsCholinergic AntagonistsPsychotropic Drugsanticholinergicspneumoniapolypharmacypotentially inappropriate medication

Identifiers

PMID38497333
PMCPMC11503537
OpenAlexW4392896952

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.