Evidence map›Paper›PMID 38497234›Full record

ArticleAge and ageing2024

What influences life expectancy in people with dementia? Social support as an emerging protective factor.

Iris Blotenberg, Melanie Boekholt, Bernhard Michalowsky, Moritz Platen, Francisca S Rodriguez, Stefan Teipel, Wolfgang Hoffmann, Jochen René Thyrian

Abstract read
In one paragraph

Article in Age and ageing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Iris BlotenbergDeutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), site Greifswald, Ellernholzstraße 1-2, 17489 Greifswald, Germany.
Melanie BoekholtDeutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), site Greifswald, Ellernholzstraße 1-2, 17489 Greifswald, Germany.ORCID 0000-0002-0576-0012
Bernhard MichalowskyDeutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), site Greifswald, Ellernholzstraße 1-2, 17489 Greifswald, Germany.ORCID 0000-0002-3425-0089
Moritz PlatenDeutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), site Greifswald, Ellernholzstraße 1-2, 17489 Greifswald, Germany.
Francisca S RodriguezDeutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), site Greifswald, Ellernholzstraße 1-2, 17489 Greifswald, Germany.ORCID 0000-0003-2919-5510
Stefan TeipelDeutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), site Rostock, Gehlsheimer Str. 20, 18147 Rostock, Germany.
Wolfgang HoffmannDeutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), site Greifswald, Ellernholzstraße 1-2, 17489 Greifswald, Germany.
Jochen René ThyrianDeutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), site Greifswald, Ellernholzstraße 1-2, 17489 Greifswald, Germany.

Funding

German Center of Neurodegenerative DiseasesUniversity Medicine of Greifswald
6 · The paper itself

Abstract

backgroundThe aim of this study was to investigate the role of support from the social environment for the life expectancy in people with dementia beyond well-established individual demographic and clinical predictors over a period of up to 8 years.

methodsThe analyses are based on data from 500 community-dwelling individuals in Germany who tested positive for dementia and were followed up for up to 8 years. Life expectancy was examined in relation to perceived social support as well as well-established socio-demographic (age, sex) and clinical predictors (cognitive status, functional status, comorbidities), using Cox regressions.

resultsGreater support from the social environment reduced the risk of mortality (hazard ratio [HR]: 0.78; 95% confidence interval [CI]: 0.63-0.98), with the role of emotional support being particularly important. Furthermore, higher age was associated with an increased mortality risk (HR: 1.08; 95% CI: 1.05-1.11), while female sex (HR: 0.64; 95% CI: 0.48-0.85) and higher cognitive (HR: 0.96; 95% CI: 0.93-0.98) and functional status (HR: 0.91; 95% CI: 0.86-0.97) were associated with higher life expectancy.

conclusionOur study provides novel evidence that less support from the social environment, especially emotional support, is a risk factor for shorter life expectancy in people with dementia-beyond known clinical factors. Not only the clinical and caregiving needs but also their psychosocial needs of individuals with dementia should be emphasised.

Indexed as

DementiaFemaleHumansLife ExpectancyProportional Hazards ModelsProtective FactorsSocial Supportcommunitydementiaemotional supportlongitudinal studymortalityolder peopleprimary carerisk factorsocial environment

Identifiers

PMID38497234
PMCPMC10945357

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.