Evidence map›Paper›PMID 38496910›Full record

ArticleNeuro-oncology practice2024

RT-PCR assay to detect

Loudy P Priesterbach-Ackley, Joyce van Kuik, Bastiaan B J Tops, Anna Lasorella, Antonio Iavarone, Wim van Hecke, Pierre A Robe, Pieter Wesseling, Wendy W J de Leng

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuro-oncology practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Recent Advances in Targeted Therapies for Adult Gliomas.Current neurology and neuroscience reports · 2026
    Review
  2. Article
  3. Diffuse glioma withRadiology case reports · 2025
    Article
  4. Diffuse Gliomas withCancers · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Loudy P Priesterbach-AckleyDepartment of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-3480-634X
Joyce van KuikDepartment of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.
Bastiaan B J TopsPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-1699-8210
Anna LasorellaDepartment of Biochemistry and Molecular Biology, Sylvester Comprehensive Cancer Center, University of Miami, Miller School of Medicine, Miami, Florida, USA.ORCID https://orcid.org/0000-0002-1839-5421
Antonio IavaroneDepartment of Neurological Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miller School of Medicine, Miami, Florida, USA.ORCID https://orcid.org/0000-0002-0683-4634
Wim van HeckeDepartment of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0003-1529-4219
Pierre A RobeDepartment of Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-7845-6196
Pieter WesselingPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-5453-5201
Wendy W J de LengDepartment of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0003-2911-6018
University Medical Center Utrecht · NLPrincess Máxima Center · NLUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: One targeted treatment option for isocitrate dehydrogenase ( Aim: To develop an RT-PCR assay to determine Methods: Twelve tissue microarrays with 353 historical glioblastoma samples were immunohistochemically stained for FGFR3. Samples with overexpression of FGFR3 ( Results: Using RT-PCR on FFPE material of the 13 samples with FGFR3 overexpression, we detected an Conclusions: RT-PCR for

Indexed as

FFPEFGFR3::TACC3 fusionglioblastomaRT-PCR

Identifiers

PMID38496910
PMCPMC10940835
OpenAlexW4390617795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.