Evidence map›Paper›PMID 38496823›Full record

ArticleEuropean urology open science2024

Clinical Validation of the Proenkephalin (

Hyunho Han, Tae Jeong Oh, Ji Eun Heo, Jongsoo Lee, Won Sik Jang, Seung Hwan Lee, Won Sik Ham, Jaehee Hwang, Sungwhan An, Young-Deuk Choi

Open access · goldAbstract read
In one paragraph

Article in European urology open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Translational andrology and urology · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hyunho HanDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Tae Jeong OhGenomictree, Inc., Daejeon, Republic of Korea.
Ji Eun HeoDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jongsoo LeeDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Won Sik JangDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Seung Hwan LeeDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Won Sik HamDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jaehee HwangGenomictree, Inc., Daejeon, Republic of Korea.
Sungwhan AnGenomictree, Inc., Daejeon, Republic of Korea.
Young-Deuk ChoiDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: To assess the effectiveness of a urine-based proenkephalin ( Methods: We first conducted a retrospective case-control study involving 54 patients with primary BC and 29 healthy individuals. We then prospectively enrolled 186 patients (January to December 2022) undergoing cystoscopy surveillance after transurethral resection of bladder tumor, of whom 59 had recurrent tumors. We analyzed voided urine samples for Key findings and limitations: In the case-control study, the Conclusions and clinical implications: The me Patient summary: We found that a test used to analyze urine samples showed good performance in detecting recurrence of NMIBC. This noninvasive me

Indexed as

Bladder cancerMolecular biomarkerPENK methylationSurveillanceUrine-derived DNA

Identifiers

PMID38496823
PMCPMC10940910
OpenAlexW4392574325

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.