Evidence map›Paper›PMID 38496662›Full record

ArticlebioRxiv : the preprint server for biology2024

Sarm1 is not necessary for activation of neuron-intrinsic growth programs yet required for the Schwann cell repair response and peripheral nerve regeneration.

Ligia B Schmitd, Hannah Hafner, Ayobami Ward, Elham Asghari Adib, Natalia P Biscola, Rafi Kohen, Manav Patel, Rachel E Williamson, Emily Desai, Julianna Bennett and 13 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 7 institutions in 1 country.

Ligia B SchmitdDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor MI, USA.ORCID 0000-0003-1570-6543
Hannah HafnerDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor MI, USA.
Ayobami WardDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor MI, USA.
Elham Asghari AdibDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
Natalia P BiscolaDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Rafi KohenDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor MI, USA.
Manav PatelDepartment of Biology, Ball State University, Muncie IN, USA.
Rachel E WilliamsonDepartment of Biology, Ball State University, Muncie IN, USA.
Emily DesaiDepartment of Biology, Ball State University, Muncie IN, USA.
Julianna BennettDepartment of Biology, Ball State University, Muncie IN, USA.
Grace SaxmanDepartment of Biology, Ball State University, Muncie IN, USA.
Mitre AthaiyaDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor MI, USA.
David WilbornDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor MI, USA.
Jaisha ShumpertDepartment of Biology, Ball State University, Muncie IN, USA.
Xiao-Feng ZhaoDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor MI, USA.
Riki KawaguchiDepartment of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Daniel H GeschwindDepartment of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Ahmet HokeDepartment of Neurology, The Johns Hopkins University, Baltimore, MD, USA.
Peter ShragerDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, USA.
Catherine A CollinsDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
Leif A HavtonDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ashley L KalinskiDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor MI, USA.ORCID 0000-0001-7611-0810
Roman J GigerDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor MI, USA.ORCID 0000-0002-2926-3336
University of Michigan · USBall State University · USUniversity of California, Los Angeles · USIcahn School of Medicine at Mount Sinai · USJames J. Peters VA Medical Center · USJohns Hopkins University · USUniversity of Rochester Medical Center · US

Funding

Tissue Engineering and RegenerationT32DE007057 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID H. KOHN · 1985 to 2026
$17.3M
Inhibitors of Synaptogenesis and Mental HealthR01MH119346 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GIGER, ROMAN JENO · 2019 to 2023
$2.6M
Regenerative and degenerative responses to axonal injuryR56NS069844 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, CATHERINE A · 2020 to 2020
$546k
Regulation of Neuroinflammation after Peripheral Nerve InjuryR15NS128837 · NINDS · BALL STATE UNIVERSITY · PI KALINSKI, ASHLEY L, ROOSSIEN, DOUGLAS HOWARD · 2023 to 2023
$447k
The contribution of macrophage subpopulations to axon degeneration, nerve inflammation, and regeneration of the injured sciatic nerveF31NS135919 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HAFNER, HANNAH JULE · 2024 to 2025
$82k
NIDCR NIH HHS T32 DE007057NIMH NIH HHS R01 MH119346NINDS NIH HHS F31 NS135919NINDS NIH HHS R15 NS128837NINDS NIH HHS R56 NS069844
6 · The paper itself

Abstract

Upon peripheral nervous system (PNS) injury, severed axons undergo rapid SARM1-dependent Wallerian degeneration (WD). In mammals, the role of SARM1 in PNS regeneration, however, is unknown. Here we demonstrate that

Identifiers

PMID38496662
PMCPMC10942360
OpenAlexW4392604092

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.