Evidence map›Paper›PMID 38496579›Full record

ArticlebioRxiv : the preprint server for biology2024

Fibroblasts as an in vitro model of circadian genetic and genomic studies: A temporal analysis.

Marcelo Francia, Merel Bot, Toni Boltz, Juan F De la Hoz, Marco Boks, René Kahn, Roel Ophoff

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Marcelo FranciaInterdepartmental Program for Neuroscience, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0001-9388-552X
Merel BotCenter for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA.
Toni BoltzDepartment of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0003-0226-7924
Juan F De la HozBioinformatics Interdepartamental Program, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-5584-7511
Marco BoksBrain Center University Medical Center Utrecht, Department Psychiatry, University Utrecht,Utrecht, The Netherlands.ORCID 0000-0001-6163-7484
René KahnBrain Center University Medical Center Utrecht, Department Psychiatry, University Utrecht,Utrecht, The Netherlands.
Roel OphoffCenter for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA.ORCID 0000-0002-8287-6457
University of California, Los Angeles · USUtrecht University · NL

Funding

Genomic Studies of Bipolar Disorder in a Large Cohort from The NetherlandsR01MH090553 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OPHOFF, ROEL A · 2010 to 2014
$6.0M
Joint genomic and statistical analyses of schizophrenia and bipolar to decipher genetic susceptibilityR01MH115676 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Roel A Ophoff, Bogdan Pasaniuc · 2018 to 2026
$5.9M
Training Grant in Neurobehavioral GeneticsT32NS048004 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARDEN, CARRIE E, OPHOFF, ROEL A · 2004 to 2025
$5.8M
NIMH NIH HHS R01 MH090553NIMH NIH HHS R01 MH115676NINDS NIH HHS T32 NS048004
6 · The paper itself

Abstract

Bipolar disorder (BD) is a heritable disorder characterized by shifts in mood that manifest in manic or depressive episodes. Clinical studies have identified abnormalities of the circadian system in BD patients as a hallmark of underlying pathophysiology. Fibroblasts are a well-established

Identifiers

PMID38496579
PMCPMC10942276
OpenAlexW4377232999

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.