Evidence map›Paper›PMID 38496569›Full record

ArticlebioRxiv : the preprint server for biology2024

Epithelial heme oxygenase-1 enhances colonic tumorigenesis by inhibiting ferroptosis.

Rosemary C Callahan, Geetha Bhagavatula, Jillian Curry, Alyse W Staley, Rachel E M Schaefer, Faiz Minhajuddin, Liheng Zhou, Rane Neuhart, Shaikh M Atif, David J Orlicky and 6 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Rosemary C Callahan
Geetha Bhagavatula
Jillian Curry
Alyse W Staley
Rachel E M Schaefer
Faiz Minhajuddin
Liheng Zhou
Rane Neuhart
Shaikh M Atif
David J Orlicky
Ian M Cartwright
Mark Gerich
Arianne L Theiss
Caroline H T Hall
Sean P Colgan
Joseph C Onyiah
University of Colorado Denver · USChildren's Hospital Colorado · USUniversity of Colorado Cancer Center · US

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
ROLE OF EPITHELIA IN ISCHEMIA/REPERFUSION INJURYR01DK050189 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI COLGAN, SEAN P · 2000 to 2024
$5.0M
Mechanisms of Adenosine ProtectionR01DK095491 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Sean P Colgan · 2012 to 2026
$4.9M
Mitochondrial Dysfunction and Mitophagy in IleitisR01DK117001 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI THEISS, ARIANNE L · 2018 to 2022
$1.9M
METABOLIC CONTROL OF EPITHELIAL AUTOPHAGY DURING INFLAMMATIONR01DK103712 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI COLGAN, SEAN P · 2015 to 2019
$1.7M
BLRD Research Career Scientist Award ApplicationIK6BX006475 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI Sean P Colgan · 2024 to 2026
–
Control of Inflammatory Acidity in Mucosal InflammationIK2BX005710 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI Ian Michael Cartwright · 2022 to 2026
–
Adipose Tissue Extracellular Vesicles in Colorectal TumorigenesisI01BX005288 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI ARIANNE L THEISS · 2022 to 2027
–
Metabolic Regulation of Mucosal InflammationI01BX002182 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI COLGAN, SEAN P · 2014 to 2025
–
BLRD VA I01 BX002182BLRD VA I01 BX005288BLRD VA IK2 BX003865BLRD VA IK2 BX005710BLRD VA IK6 BX006475NIDDK NIH HHS R01 DK050189NIDDK NIH HHS R01 DK095491NIDDK NIH HHS R01 DK103712NIDDK NIH HHS R01 DK117001
6 · The paper itself

Abstract

Colorectal cancer has been linked to chronic colitis and red meat consumption, which can increase colonic iron and heme. Heme oxygenase-1 (

Identifiers

PMID38496569
PMCPMC10942430
OpenAlexW4392632308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.