Evidence map›Paper›PMID 38496463›Full record

ArticlebioRxiv : the preprint server for biology2024

Efficient and multiplexed somatic genome editing with Cas12a mice.

Jess D Hebert, Haiqing Xu, Yuning J Tang, Paloma A Ruiz, Colin R Detrick, Jing Wang, Nicholas W Hughes, Oscar Donosa, Laura Andrejka, Saswati Karmakar and 6 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Yuning J Tang
Colin R Detrick
Jing Wang
Nicholas W Hughes
Oscar Donosa
Irenosen Aboiralor
Rui Tang
Stanford University · USChan Zuckerberg Initiative (United States) · US

Funding

Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI MICHAEL KENNEY · 2007 to 2026
$71.4M
(PQ4) Quantitative and multiplexed analysis of gene function in cancer in vivoR01CA231253 · NCI · STANFORD UNIVERSITY · PI PETROV, DMITRI, WINSLOW, MONTE MEIER · 2018 to 2022
$2.3M
Genetic dissection of oncogenic Kras signalingR01CA230025 · NCI · STANFORD UNIVERSITY · PI WINSLOW, MONTE MEIER · 2021 to 2025
$2.2M
NCI NIH HHS P30 CA124435NCI NIH HHS R01 CA230025NCI NIH HHS R01 CA231253
6 · The paper itself

Abstract

Somatic genome editing in mouse models has increased our understanding of the

Identifiers

PMID38496463
PMCPMC10942438
OpenAlexW4392578137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.