Evidence map›Paper›PMID 38496438›Full record

ArticlebioRxiv : the preprint server for biology2024

Tuft cell IL-17RB restrains IL-25 bioavailability and reveals context-dependent ILC2 hypoproliferation.

Xiaogang Feng, Tilde Andersson, Julia Gschwend, Pascal Flüchter, Ivan Berest, Julian L Muff, Daniele Carchidi, Antonie Lechner, Jeshua C de Tenorio, Nina Brander and 6 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 3 countries.

Xiaogang Feng
Tilde Andersson
Julia Gschwend
Pascal Flüchter
Ivan Berest
Julian L Muff
Daniele Carchidi
Antonie Lechner
Jeshua C de Tenorio
Nina Brander
Ulrich Boehm
Christoph S N Klose
David Artis
Trese Leinders-ZufallORCID 0000-0002-0678-362X
Frank Zufall
Christoph SchneiderORCID 0000-0002-0452-2960
University of Zurich · CHSaarland University · DECornell University · USETH Zurich · CHHumboldt-Universität zu Berlin · DE

Funding

Neuroimmune Regulation of Atopic DermatitisR01AR070116 · NIAMS · WASHINGTON UNIVERSITY · PI KIM, BRIAN · 2016 to 2021
$3.8M
NIAMS NIH HHS R01 AR070116
6 · The paper itself

Abstract

The tuft cell-ILC2 circuit orchestrates rapid type 2 responses upon detecting microbe-derived succinate and luminal helminths. Our findings delineate key mechanistic steps, involving IP3R2 engagement and Ca

Identifiers

PMID38496438
PMCPMC10942319
OpenAlexW4392578335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.