Evidence map›Paper›PMID 38496185›Full record

ReviewCureus2024

The Protective Effect of Abortion on Preeclampsia: An Analysis of Current Research.

Sarah J Norman, Gena Fontus, Chancée Forestier, Tasneem Hiba, Stephanie Colon Pagan, Michael Osondu, Volha Shylovich

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sarah J NormanMedicine, American University of the Caribbean School of Medicine, Cupecoy, SXM.
Gena FontusMedicine, American University of the Caribbean School of Medicine, Cupecoy, SXM.
Chancée ForestierMedical School, Ascension Providence Hospital, Southfield, USA.
Tasneem HibaMedicine, American University of the Caribbean School of Medicine, Cupecoy, SXM.
Stephanie Colon PaganMedicine, American University of the Caribbean School of Medicine, Cupecoy, SXM.
Michael OsonduMedicine, American University of the Caribbean School of Medicine, Cupecoy, SXM.
Volha ShylovichObstetrics and Gynecology, BronxCare Health System, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A review of the current literature on preeclampsia (PE) confirms that this pregnancy complication remains a common cause of maternal mortality. Within the last several decades, obstetric and gynecological researchers worldwide have indicated an association between prior abortions and the development of PE. Different studies have debated whether abortion is a protective or risk factor for PE. However, the most current literature demonstrates a stronger likelihood that a positive history of abortions will offer a protective effect against PE. This association has been supported by advancements in the reproductive immunology literature, which states complex fetal and paternal pathological mechanisms help to build maternal immunological tolerance, thus protecting expectant mothers from pregnancy complications. This literature review will compare studies supporting prior abortions offering a protective effect against PE with those stating prior abortions are a risk factor for the development of PE. Additionally, this critical review will discuss the advancements and current understanding of reproductive immunology and how it pertains to this association between positive abortion history and PE.

Indexed as

eclampsiainduced abortionmaternal immune tolerancepreeclampsiapreeclampsia-eclampsiareproductive immunologyspontaneous abortion

Identifiers

PMID38496185
PMCPMC10942113

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.