ArticleCureus2024
Trends in Syphilis in Pregnant Women in Japan in 2016 and 2022.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 5 citations in OpenAlex.
- Incidence of Jarisch-Herxheimer reaction after syphilis treatment and the role of awareness effect.Journal of the Chinese Medical Association : JCMA · 2026Article
- Epidemiological trends and spatiotemporal distribution of syphilis in Nagasaki Prefecture, Japan, 2014-2023.Frontiers in public health · 2026Article
- Assessing progress towards the elimination of mother-to-child transmission of syphilis in Peru: A national retrospective analysis.PLOS global public health · 2026Article
- Syphilis in Pregnant Women and Congenital Syphilis in Japan, 2022 to 2023: A Warning for Other Countries.Sexually transmitted diseases · 2025Article
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Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since 2012, the rate of syphilis infection has increased dramatically in high-income countries including Japan. In this study, we examined the rate of syphilis infection among pregnant women and perinatal outcomes in the syphilis-infected pregnancy in 2022 in Japan, and compared the results with those in 2016. We requested 2,005 obstetric institutes to provide information on syphilis infection in pregnant women who delivered in 2022. A total of 1,346 obstetrical facilities responded with valid information. We compared the results with those in our previous study. The prevalence of syphilis-infected pregnant women was 1/1,215. The incidence of preterm delivery, intrauterine fetal demise and congenital syphilis in surviving neonates in the syphilis-infected pregnancy were 9%, 2% and 7%, respectively. The prevalence of syphilis-infected pregnant women has increased significantly, while the incidence of congenital syphilis seems to have decreased clinically.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.