Evidence map›Paper›PMID 38495814›Full record

ArticleBJR open2022

The reproducibility of manual RV/LV ratio measurement on CT pulmonary angiography.

Sarah Lanham, Ahmed Maiter, Andrew J Swift, Krit Dwivedi, Samer Alabed, Oscar Evans, Michael J Sharkey, Suzanne Matthews, Christopher S Johns

Open access · goldAbstract read
In one paragraph

Article in BJR open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sarah LanhamDepartment of Clinical Radiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Ahmed MaiterDepartment of Clinical Radiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Andrew J SwiftDepartment of Clinical Radiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Krit DwivediDepartment of Clinical Radiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Samer AlabedDepartment of Clinical Radiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Oscar EvansDepartment of Clinical Radiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Michael J SharkeyDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.
Suzanne MatthewsDepartment of Clinical Radiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Christopher S JohnsDepartment of Clinical Radiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Sheffield Teaching Hospitals NHS Foundation Trust · GBInsigneo · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Objectives: Right ventricular (RV) dysfunction carries elevated risk in acute pulmonary embolism (PE). An increased ratio between the size of the right and left ventricles (RV/LV ratio) is a biomarker of RV dysfunction. This study evaluated the reproducibility of RV/LV ratio measurement on CT pulmonary angiography (CTPA). Methods: 20 inpatient CTPA scans performed to assess for acute PE were retrospectively identified from a tertiary UK centre. Each scan was evaluated by 14 radiologists who provided a qualitative overall opinion on the presence of RV dysfunction and measured the RV/LV ratio. Using a threshold of 1.0, the RV/LV ratio measurements were classified as positive (≥1.0) or negative (<1.0) for RV dysfunction. Interobserver agreement was quantified using the Fleiss κ and intraclass correlation coefficient (ICC). Results: Qualitative opinion of RV dysfunction showed weak agreement (κ = 0.42, 95% CI 0.37-0.46). The mean RV/LV ratio measurement for all cases was 1.28 ± 0.68 with significant variation between reporters ( Conclusion: Both qualitative opinion and quantitative manual RV/LV ratio measurement show poor agreement for identifying RV dysfunction on CTPA. Advances in knowledge: Caution should be exerted if using manual RV/LV ratio measurements to inform clinical risk stratification and management decisions.

Identifiers

PMID38495814
PMCPMC10941330
OpenAlexW4304146127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.