ReviewFrontiers in endocrinology2024
Surgical treatment of cryptorchidism: current insights and future directions.
Review in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed, 18 citations in OpenAlex.
- Genetic landscape of a neonatal hypogonadotropic hypogonadism series: Novel variants and phenotypic spectrum.Journal of neuroendocrinology · 2026Article
- Learning curve for second-stage laparoscopic Fowler-Stephens orchidopexy: an exploratory CUSUM analysis with prospective ultrasonographic follow-up.World journal of urology · 2026Article
- A 20-cm redundant vas deferens loop during late orchidopexy: aberrant ductal anatomy as an intraoperative pitfall in a 17-year-old male.International journal of surgery case reports · 2026Article
- Anatomical position as a predictor of hormonal therapy failure in palpable undescended testes.International urology and nephrology · 2026Article
- Management of andrological disorders from childhood and adolescence to transition age: guidelines from the Italian Society of Andrology and Sexual Medicine (SIAMS) in collaboration with the Italian Society for Pediatric Endocrinology and Diabetology (SIEDP) - part-2.Journal of endocrinological investigation · 2026Article
- Somatic cell dysfunction precedes testicular degeneration in a surgical model of cryptorchidism.Pediatric surgery international · 2026Article
- Cryptorchidism and infertility: what do we know so far?Asian journal of andrology · 2026Review
- Comparison of Scrotal Orchiopexy Versus Traditional Inguinal Orchiopexy for Palpable Undescended and Retractile Testis in Children: Insights from a Greek Surgical Center.Life (Basel, Switzerland) · 2026Article
- Prenatally diagnosed intra-abdominal testicular teratoma managed with single-stage Fowler-Stephens orchiopexy postnatally: A case report and literature review.Experimental and therapeutic medicine · 2026Article
- Modified shehata surgery vs. laparoscopic One-stage orchiopexy for intra-abdominal cryptorchidism: a comparative retrospective study.Frontiers in surgery · 2026Article
- Research progress on testicular torsion secondary to inguinal cryptorchidism.Frontiers in pediatrics · 2026Review
- Obesity and cryptorchidism across development: an integrated endocrine and metabolic life course framework.Frontiers in endocrinology · 2026Review
- Neonatal mature teratoma arising from an intra-abdominal cryptorchid testis with torsion: a case report and literature review.Frontiers in pediatrics · 2026Article
- Laparoscopic one-stage vessel-sparing orchiopexy and two-stage laparoscopic Fowler-Stephens orchiopexy: a comparative study.Frontiers in pediatrics · 2026Article
- Article
- Trend in testicular volume change after orchiopexy in 854 children with cryptorchidism.Asian journal of andrology · 2025Article
- Orchidopexy Timing and Follow Up: From Guidelines to Clinical Practice.Diagnostics (Basel, Switzerland) · 2025Article
- The timing of cryptorchidism surgery: analysis of the contradiction between guideline consensus and clinical practice implementation.Pediatric surgery international · 2025Review
- Evaluation of semen parameters and histopathological comparison of inguinal and abdominal orchiectomy specimens in late post pubertal men with unilateral undescended testis.Basic and clinical andrology · 2025Article
- Case Report: A rare case of prune belly syndrome with intraperitoneal cryptorchidism.Frontiers in pediatrics · 2025Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cryptorchidism presents with an incidence of 1-5% with potential long-term implications on future fertility and overall health. This review focuses on surgical treatment modalities, their impact on testicular development, and function while addressing the Nordic consensus statement as well as current European Association of Urology (EAU) and American Urological Association (AUA) guidelines. Congenital and acquired cryptorchidism present distinctive challenges in surgical management, with different implications for fertility. While congenital cryptorchidism entails a risk to fertility and warrants early intervention, both retractile testes and acquired cryptorchidism also pose risks to fertility potential, underscoring the importance of evaluating treatment options. Testicular location and the child's age form the basis of a practical classification system for undescended testicles. Early diagnosis by clinical examination enables timely treatment. Imaging is reserved for selected cases only. Following guidelines, orchidopexy is recommended between 6-12 months of age for congenital cryptorchidism. Evidence increasingly suggests the benefits of early surgery for promoting testicular health and fertility potential. Current surgical options range from open to laparoscopic techniques, with the choice largely determined by the location and accessibility of the undescended testicle. The advancement in laparoscopic approaches for non-palpable testes underscores the evolving landscape of surgical treatment. Sequential surgeries may be required depending on the mobility of the undescended testes. More research is needed to explore both the potential and limitations of hormonal therapy, which is secondary to surgical treatment and can selectively have a role as adjunct to surgery. Long-term follow-up is imperative to evaluate fertility outcomes, risk of testicular malignancy, and psychological impact. By integrating current guidelines with the latest evidence, this review intends to facilitate a comprehensive understanding of cryptorchidism, thereby optimizing patient management and outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.